3.1.2.4: 3-hydroxyisobutyryl-CoA hydrolase

This is an abbreviated version!
For detailed information about 3-hydroxyisobutyryl-CoA hydrolase, go to the full flat file.

Word Map on EC 3.1.2.4

3.1.2.4

valine

leigh

methacrylyl-coa

leigh-like

dystonia

enoyl-coa

crotonase

3-hydroxyisobutyrate

Reaction

Synonyms

3-hydroxy-isobutyryl CoA hydrolase, 3-hydroxyisobutyryl-CoA hydrolase, BCH, beta-hydroxyisobutyryl-CoA hydrolase, beta-hydroxyisobutyryl-coenzyme A hydrolase, CHY1, HIB CoA hydrolase, HIB-CoA hydrolase, HIBCH, HIBYL-CoA hydrolase, HICH, hydrolase, 3-hydroxyisobutyryl coenzyme A, More, NGR_b20860, Smb20752, VutE

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.2 Thioester hydrolases

3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase

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Results	in table
2394	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
161	Disease/ Diagnostics
16	General Information
17	Inhibitors
8	Ki Value [mM]
5	KM Value [mM]
4	Localization
1	Metals/Ions
7	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
22	Organism
12	Pathway
17	PDB ID
6	pH Optimum
3	pH Range
4	Protein Variants
5	Purification (Commentary)
2	Reaction
5	Reaction Type
20	Reference
23	Source Tissue
6	Specific Activity [micromol/min/mg]
41	Substrates and Products (Substrate)
6	Subunits
28	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Turnover Number [1/s]

KM Value

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KM Value on EC 3.1.2.4 - 3-hydroxyisobutyryl-CoA hydrolase

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0.006

(S)-3-hydroxy-2-methylpropanoyl-CoA

Homo sapiens

recombinant enzyme, pH 8.0, 30°C

653127

0.006

3-hydroxy-2-methylpropanoyl-CoA

Rattus norvegicus

94558

0.025

3-hydroxypropionyl-CoA

2 entries

0.0029

cinnamoyl-CoA

Arabidopsis thaliana

Q9LKJ1

at 30°C, in 50 mM Tris/HCl buffer, pH 7.0

710261