3.1.13.3: oligonucleotidase

This is an abbreviated version!
For detailed information about oligonucleotidase, go to the full flat file.

Reaction

exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates =

Synonyms

CpsORN, EC 3.1.4.19, More, nanoRNase, NrnC, nucleotidase, oligo-, oligoribonuclease, ORN, phosphodiesterase, REXO2, RNase T, small fragment nuclease, XC847, YtqI

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.13 Exoribonucleases producing 5′-phosphomonoesters

                3.1.13.3 oligonucleotidase

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Results	in table
202	AA Sequence
3	Application
1	CAS Registry Number
14	Cloned(Commentary)
6	Crystallization (Commentary)
21	Disease/ Diagnostics
36	General Information
27	Inhibitors
3	Ki Value [mM]
14	KM Value [mM]
3	Localization
25	Metals/Ions
7	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
41	Organism
13	pH Optimum
3	pH Range
26	Protein Variants
15	Purification (Commentary)
3	Reaction
1	Reaction Type
41	Reference
1	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
119	Substrates and Products (Substrate)
15	Subunits
53	Synonyms
9	Temperature Optimum [°C]
4	Temperature Stability [°C]
10	Turnover Number [1/s]

Disease

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Disease on EC 3.1.13.3 - oligonucleotidase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Carcinogenesis

Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma.

32354376

exodeoxyribonuclease (lambda-induced) deficiency

Identification of RNase T as a high-copy suppressor of the UV sensitivity associated with single-strand DNA exonuclease deficiency in Escherichia coli.

10049912

Glioma

RUNX1 and REXO2 are associated with the heterogeneity and prognosis of IDH wild type lower grade glioma.

34088969

Lyme Disease

The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains.

9396823

Neoplasms

RUNX1 and REXO2 are associated with the heterogeneity and prognosis of IDH wild type lower grade glioma.

34088969

Neoplasms

The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains.

9396823

Pheochromocytoma

Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma.

32354376

Starvation

RNase T affects Escherichia coli growth and recovery from metabolic stress.

1704882

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