3.1.1.77: acyloxyacyl hydrolase
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For detailed information about acyloxyacyl hydrolase, go to the full flat file.
Reaction
Synonyms
acyloxyacyl hydrolase, AOAH, neutrophil acyloxyacyl hydrolase
ECTree
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Engineering
Engineering on EC 3.1.1.77 - acyloxyacyl hydrolase
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additional information
AOAH-deficient (Aoah-/-) mice, recovery from the tolerant state induced by Gram-negative bacteria is greatly delayed in mice that lack acyloxyacyl hydrolase (AOAH). Wild-type mice regain normal responsiveness within 14 days after they receive an intraperitoneal injection of LPS or Gram-negative bacteria, AOAH-deficient mice have greatly reduced proinflammatory responses to a second LPS injection for at least 3 weeks