3.1.1.63: 11-cis-retinyl-palmitate hydrolase
This is an abbreviated version!
For detailed information about 11-cis-retinyl-palmitate hydrolase, go to the full flat file.
Reaction
ECTree
3.1.1.63 11-cis-retinyl-palmitate hydrolaseAdvanced search results
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Substrates Products on EC 3.1.1.63 - 11-cis-retinyl-palmitate hydrolase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
11-cis-retinyl palmitate + H2O
11-cis-retinol + palmitate
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all-trans-retinyl palmitate is hydrolyzed with higher specificity
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?
additional information
?
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the 11-cis-isomer is hydrolyzed at a much higher rate than the other isomers, 9-cis, 13-cis, and all-trans-retinyl palmitate
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?
additional information
?
-
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all-trans-retinyl palmitate and cholesteryl oleate may be hydrolyzed at the same non-specific catalytic site, it is very likely that 11-cis-retinyl palmitate is hydrolyzed at a discrete catalytic site
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?
additional information
?
-
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also hydrolyzes all-trans-retinol with lower activity
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?
additional information
?
-
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the hydrolysis of 11-cis retinyl esters in the retinal pigment epithelium membrane constitutes a novel pathway of visual chromophore biosynthesis
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?
