3.1.1.52: phosphatidylinositol deacylase

This is an abbreviated version!
For detailed information about phosphatidylinositol deacylase, go to the full flat file.

Word Map on EC 3.1.1.52

Reaction

1-phosphatidyl-D-myo-inositol
+
H2O
=
1-acylglycerophosphoinositol
+
a carboxylate

Synonyms

phosphatidylinositol phospholipase A2, phospholipase A2, phosphatidylinositol, cPLA2alpha, group IVA cytosolic phospholipase A2alpha

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.52 phosphatidylinositol deacylase

Substrates Products

Substrates Products on EC 3.1.1.52 - phosphatidylinositol deacylase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-acyl-2-arachidonoyl-sn-glycerol-3-phosphoinositol + H2O
1-acylglycerophosphoinositol + arachidonic acid
show the reaction diagram
1-acyl-2-arachidonoyl-sn-glycerol-3-phosphoinositol + H2O
?
show the reaction diagram
-
release of arachidonic acid for subsequent metabolic activity in macrophages
-
-
?
1-acyl-2-oleoyl-sn-glycerol 3-phosphate + H2O
1-acylglycerol 3-phosphate + oleic acid
show the reaction diagram
-
32.6% of 1-acyl-2-oleoyl-sn-glycerol-3-phosphorylinositol
-
?
1-acyl-2-oleoyl-sn-glycerol-3-phosphocholine + H2O
1-acylglycerol-3-phosphorylcholine + oleic acid
show the reaction diagram
-
62.5% of 1-acyl-2-oleoyl-sn-glycerol-3-phosphorylinositol
-
?
1-acyl-2-oleoyl-sn-glycerol-3-phosphoinositol + H2O
1-acylglycerophosphoinositol + oleic acid
show the reaction diagram
1-acyl-2-oleoyl-sn-glycerol-3-phosphorylethanolamine + H2O
1-acylglycerol-3-phosphorylethanolamine + oleic acid
show the reaction diagram
-
25.1% of 1-acyl-2-oleoyl-sn-glycerol-3-phosphorylinositol
-
?
1-acyl-2-oleoyl-sn-glycerol-3-phosphorylserine + H2O
1-acylglycerol-3-phosphorylserine + oleic acid
show the reaction diagram
-
21.51% of 1-acyl-2-oleoyl-sn-glycerol-3-phosphorylinositol
-
?
1-acyl-2-palmitoyl-sn-glycerol-3-phosphoinositol + H2O
1-acylglycerophosphoinositol + palmitic acid
show the reaction diagram
-
-
-
?
1-acyl-2-stearoyl-sn-glycerol-3-phosphoinositol + H2O
1-acylglycerophosphoinositol + stearic acid
show the reaction diagram
-
-
-
?
1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine + H2O
arachidonic acid + 1-palmitoyl-sn-glycero-3-phosphocholine
show the reaction diagram
-
2 min, 37°C (pre-warmed), in presence of 0.5 mg/ml bovine serum albumin and various concentrations of calcium
quantification of release of radio-labelled arachidonic acid
-
?