3.1.1.37: steroid-lactonase

This is an abbreviated version!
For detailed information about steroid-lactonase, go to the full flat file.

Reaction

testololactone
+
H2O
=
testolate

Synonyms

lactonase, steroid, steroid lactonase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.37 steroid-lactonase

Substrates Products

Substrates Products on EC 3.1.1.37 - steroid-lactonase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
16alpha-hydroxytestololactone + H2O
16alpha-hydroxytestolate
show the reaction diagram
-
50% the rate of testololactone
-
?
testolate
testololactone + H2O
show the reaction diagram
-
lactone formation more rapidly than lactone hydrolysis, only at pH 6, presence of Mn2+
-
r
testololactone + H2O
?
show the reaction diagram
-
-
-
-
?
testololactone + H2O
testolate
show the reaction diagram
-
-
-
r
additional information
?
-
-
not: steroids containing gamma-lactones, digitoxigenin, spirolactone
-
-
?