3.1.1.31: 6-phosphogluconolactonase

This is an abbreviated version!
For detailed information about 6-phosphogluconolactonase, go to the full flat file.

Reaction

6-phospho-D-glucono-1,5-lactone
+
H2O
=
6-phospho-D-gluconate

Synonyms

lactonase, phosphoglucono-, phosphogluconolactonase, 6-phosphoglucono-gamma-lactonase, 6-phospho-D-glucose-delta-lactone hydrolase, 6-PGL, PGL, 6PGL, glucose-6-phosphate dehydrognease-6-phosphogluconolactonase, G6PD-6PGL, Glc6PD-6PGL, 6-phosphogluconolactonase, 6-phosphonogluconolactonase, 6PGL-G6PDH, Pf6PGL, YbhE protein, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, Xoo2316, PGL1, PGL2, PGL3, PGL4, PGL5, GluPho, PglA, 6-phosphogluconolactonase 3, PF14_0511, OG1RF_11582, GL50803_8682

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.31 6-phosphogluconolactonase

Inhibitors

Inhibitors on EC 3.1.1.31 - 6-phosphogluconolactonase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(NH4)2SO4
-
0.06 M, 55% inhibition
ellagic acid
mixed type inhibitor of glucose 6-phosphate activity
glucose-6-phosphate
-
competitive
glutathione
-
PfGluPho is inhibited by S-glutathionylation
guanidine hydrochloride
inhibitory at 0.2 M, 40% inhibition at 0.4 M, 65% inhibition at 0.5 M
additional information
-