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3.1.1.31: 6-phosphogluconolactonase

This is an abbreviated version!
For detailed information about 6-phosphogluconolactonase, go to the full flat file.

Reaction

6-phospho-D-glucono-1,5-lactone
+
H2O
=
6-phospho-D-gluconate

Synonyms

6-PGL, 6-phospho-D-glucose-delta-lactone hydrolase, 6-phosphoglucono-gamma-lactonase, 6-phosphogluconolactonase, 6-phosphogluconolactonase 3, 6-phosphonogluconolactonase, 6PGL, 6PGL-G6PDH, G6PD-6PGL, GL50803_8682, Glc6PD-6PGL, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, glucose-6-phosphate dehydrognease-6-phosphogluconolactonase, GluPho, lactonase, phosphoglucono-, OG1RF_11582, PF14_0511, Pf6PGL, PGL, PGL1, PGL2, PGL3, PGL4, PGL5, PglA, phosphogluconolactonase, Xoo2316, YbhE protein

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.31 6-phosphogluconolactonase

Disease

Disease on EC 3.1.1.31 - 6-phosphogluconolactonase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
6-phosphogluconolactonase deficiency
6-Phosphogluconolactonase deficiency, a hereditary erythrocyte enzyme deficiency: possible interaction with glucose-6-phosphate dehydrogenase deficiency.
Anemia, Hemolytic
6-Phosphogluconolactonase deficiency, a hereditary erythrocyte enzyme deficiency: possible interaction with glucose-6-phosphate dehydrogenase deficiency.
Brain Neoplasms
Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized ?-[1-13C]gluconolactone.
Breast Neoplasms
Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer.
Molecular-assisted immunohistochemical optimization.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
6-Phosphogluconolactonase deficiency, a hereditary erythrocyte enzyme deficiency: possible interaction with glucose-6-phosphate dehydrogenase deficiency.
Glucosephosphate Dehydrogenase Deficiency
6-Phosphogluconolactonase deficiency, a hereditary erythrocyte enzyme deficiency: possible interaction with glucose-6-phosphate dehydrogenase deficiency.
Computer simulation of the metabolic consequences of the combined deficiency of 6-phosphogluconolactonase and glucose-6-phosphate dehydrogenase in human erythrocytes.
Malaria
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase. A novel bifunctional enzyme in malaria parasites.
Neoplasm Metastasis
Differential Site-Based Expression of Pentose Phosphate Pathway-Related Proteins among Breast Cancer Metastases.
Neoplasms
Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer.
Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized ?-[1-13C]gluconolactone.
Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping.
Pancreatic Neoplasms
Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine.