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3.1.1.23: acylglycerol lipase

This is an abbreviated version!
For detailed information about acylglycerol lipase, go to the full flat file.

Word Map on EC 3.1.1.23

Reaction

CnHmCO-C3O3H7
+
H2O
=
CnHmCO2H
+
glycerol

Synonyms

AtMAGL, AtMAGL1, AtMAGL10, AtMAGL11, AtMAGL14, AtMAGL15, AtMAGL16, AtMAGL2, AtMAGL3, AtMAGL4, AtMAGL5, AtMAGL6, AtMAGL7, AtMAGL8, AtMAGL9, fatty acyl monoester lipase, glycerol-monoester acylhydrolase, HMGL, LH57_01015, lipase, lipase G, LipB, lipozyme IM, MAG hydrolase, MAG lipase, MAGL, MAGL-cy, MAGL-m, MAGL16, MAGL6, MAGL8, MGH, MGL, MGL Rv0183, MGL-like activity, MGLL, MGLP, monoacylglycerol hydrolase, monoacylglycerol lipase, monoglycerid lipase, monoglyceridase, monoglyceride hydrolase, monoglyceride lipase, monoglyceride lipase-like activity, monoglyceridyllipase, MSMEG_0220, mtbMGL, patatin-like protein 1, patatin-like protein 16, patatin-like protein 2, patatin-like protein 3, patatin-like protein 4, patatin-like protein 5, patatin-like protein 6, patatin-like protein 7, patatin-like protein 8, patatin-like protein 9, PLP1, PLP16, PLP2, PLP3, PLP4, PLP5, PLP6, PLP7, PLP8, PLP9, Rv0183, Rv0183 protein, Yju3p

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.23 acylglycerol lipase

Specific Activity

Specific Activity on EC 3.1.1.23 - acylglycerol lipase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0298
-
with 1(3)-arachidonoylglycerol as substrate
0.0318
-
with 2-arachidonoylglycerol as substrate
0.07
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL14
0.08
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL4
0.09
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL14
0.13
purified recombinant MBP-tagged wild-type enzyme, pH 8.0-9.0, 37°C
0.14
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL10
0.16
lysophosphatidylethanolamine, pH 8.0, 38°C, AtMAGL1
0.17
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL14
0.33
lysophosphatidylethanolamine, pH 8.0, 38°C, AtMAGL2
0.38
lysophosphatidylcholine, pH 8.0, 38°C, AtMAGL4
0.41
lysophosphatidylethanolamine, pH 8.0, 38°C, AtMAGL4
0.52
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL1
0.63
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL2
1.77
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL7
12.11
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL8
143
-
recombinant enzyme, using monomyristin as substrate, at 37°C and at pH 8.0 in 2.5 mM Tris-HCl buffer, 150 mM NaCl, and 3 mM sodium taurodeoxycholate
179
-
after 6.2fold purification, using olive oil as substrate, at pH 7.4, 30°C
19.3
purified recombinant MBP-tagged wild-type enzyme, pH 8.0-9.0, 37°C
2.04
-
cytosolic fraction
21.8
purified recombinant MBP-tagged wild-type enzyme, pH 8.0-9.0, 37°C
23.93
monoacylglycerol substrate, pH 8.0, 38°C, AtMAGL6
29
-
crude enzyme, using olive oil as substrate, at pH 7.4, 30°C
290
-
purified recombinant enzyme
80
-
recombinant enzyme, using monomyristin as substrate, at 37°C and at pH 8.0 in 2.5 mM Tris-HCl buffer, 150 mM NaCl, and 3 mM sodium taurodeoxycholate
additional information