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3.1.1.2: arylesterase

This is an abbreviated version!
For detailed information about arylesterase, go to the full flat file.

Word Map on EC 3.1.1.2

Reaction

a phenyl acetate
+
H2O
=
a phenol
+
acetate

Synonyms

(R)-specific SGNH arylesterase, A-esterase, alpha-esterase, ARE, AREase, aromatic esterase, Aryl-ester hydrolase, aryldialkylphosphatase, arylesterase, DvvII, EST-1, EST-2, EST-3, ESt-A, Est0881, EstB, EstR5, G3C9 rePON1, gox0881, HDL-PON1, K-45, lp_1002, More, neuropathy target esterase-related esterase, NRE, NRECV, NTE-R1, NTE-related 1, NTE-related esterase, paraoxonase, paraoxonase 1, paraoxonase-1, paraoxonase/arylesterase, paraoxonase1, patatin-like phospholipase 7, phenyl acetate esterase, phenyl valerate esterase, PNPLA7, PON-aryl, PON1, PON1/Aryl, pyrethroid-resistance-associated esterase, Saci_2140, SacPox, serum paraoxonase/arylesterase 1, SGNH arylesterase, SGNH-arylesterase, SisLac, Sm23, Vmut2255, VmutPLL

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.2 arylesterase

Turnover Number

Turnover Number on EC 3.1.1.2 - arylesterase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4.7
1-naphthyl acetate
-
immobilized cross-linked enzyme aggregate, at pH 7.0 and 25°C
9.8
1-naphthyl butyrate
-
immobilized cross-linked enzyme aggregate, at pH 7.0 and 25°C
1
1-phenylvinyl acetate
-
4
2,2,2-trifluoroethyl acetate
-
0.82
2,2-difluoroethyl acetate
-
403
2,3-difluorophenyl acetate
-
334
2,4-difluorophenyl acetate
-
145
2,6-difluorophenyl acetate
-
0.5
2-fluoroethyl acetate
-
431
2-fluorophenyl acetate
-
0.66 - 55.2
2-naphthyl acetate
7
2-naphthyl butanoate
pH 7.0, 25°
22.7
2-naphthyl butyrate
-
immobilized cross-linked enzyme aggregate, at pH 7.0 and 25°C
51
3,4-dimethyl phenyl acetate
-
125
3-cyanophenyl acetate
-
571
3-fluorophenyl acetate
-
99
3-naphthyl acetate
pH 7.0, 25°
16.4
3-naphthyl butanoate
pH 7.0, 25°
59
3-nitrophenyl acetate
-
14
4-acetoxy methyl benzoate
-
13
4-acetoxyacetophenone
pH 8.0
26
4-acetoxybenzaldehyde
117
4-chlorophenyl acetate
-
23
4-cyanophenyl acetate
-
0.244
4-diethyl phosphate methyl benzoate
pH 8.0
0.13 - 2500
4-nitrophenyl acetate
97.2
4-nitrophenyl butanoate
pH 7.0, 25°
17.6 - 285
4-nitrophenyl butyrate
341
4-nitrophenyl caprate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
467
4-nitrophenyl caproate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
410
4-nitrophenyl caprylate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
264
4-nitrophenyl laurate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
265
4-nitrophenyl palmitate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
269
4-nitrophenyl phosphate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
61.3 - 69.5
7-aminocephalosporanic acid
450
Alpha-naphthyl acetate
recombinant wild type enzyme, in 100 mM sodium phosphate buffer (pH 7.0), at 60°C
0.0008 - 0.02
Benzyl acetate
0.27
butyl acetate
-
20.81 - 42.7
cephalosporin C
0.242
ethyl acetate
-
18
naphthalen-2-yl acetate
pH 8.0, wild-type enzyme
68
p-tolyl acetate
-
0.35 - 4778
phenyl acetate
0.4
propyl acetate
-
9.3 - 20
S-methyl thiobutanoate
additional information
additional information
-
all kinetic parameters increase with temperature, but the ratios kcat/Km and Kp/Km remain practically constant
-