3.1.1.2: arylesterase

This is an abbreviated version!
For detailed information about arylesterase, go to the full flat file.

Word Map on EC 3.1.1.2

3.1.1.2

lipoprotein

cholesterol

high-density

atherosclerosis

cardiovascular

low-density

coronary

apolipoproteins

artery

triglyceride

organophosphate

malondialdehyde

hdl-associated

lactonase

anti-oxidant

atherogenic

mellitus

c-reactive

organophosphorus

pesticide

acetylcholinesterase

phenylacetate

lipoprotein-associated

hdl-cholesterol

homocysteine

atherogenesis

esterases

cholinesterase

apoa-i

antiatherogenic

qq

ox-ldl

chlorpyrifos

atheroprotective

oxons

butyrylcholinesterase

carboxylesterase

lipoprotein-cholesterol

paf-ah

lp-pla2

phosphotriesterase

parathion

soman

analysis

clopidogrel

acetylhydrolase

drug development

allozyme

oxidant-antioxidant

sarin

lecithin:cholesterol

medicine

thiolactone

Reaction

Synonyms

(R)-specific SGNH arylesterase, A-esterase, alpha-esterase, ARE, AREase, aromatic esterase, Aryl-ester hydrolase, aryldialkylphosphatase, arylesterase, DvvII, EST-1, EST-2, EST-3, ESt-A, Est0881, EstB, EstR5, G3C9 rePON1, gox0881, HDL-PON1, K-45, lp_1002, More, neuropathy target esterase-related esterase, NRE, NRECV, NTE-R1, NTE-related 1, NTE-related esterase, paraoxonase, paraoxonase 1, paraoxonase-1, paraoxonase/arylesterase, paraoxonase1, patatin-like phospholipase 7, phenyl acetate esterase, phenyl valerate esterase, PNPLA7, PON-aryl, PON1, PON1/Aryl, pyrethroid-resistance-associated esterase, Saci_2140, SacPox, serum paraoxonase/arylesterase 1, SGNH arylesterase, SGNH-arylesterase, SisLac, Sm23, Vmut2255, VmutPLL

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.1 Carboxylic-ester hydrolases

3.1.1.2 arylesterase

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Results	in table
70	Activating Compound
2794	AA Sequence
30	Application
1	CAS Registry Number
34	Cloned(Commentary)
7	Crystallization (Commentary)
6016	Disease/ Diagnostics
14	Expression
11	General Information
3	General Stability
160	Inhibitors
36	kcat/KM [mM/s]
5	Ki Value [mM]
145	KM Value [mM]
12	Localization
49	Metals/Ions
58	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
37	Organic Solvent Stability
181	Organism
5	Pathway
66	PDB ID
44	pH Optimum
8	pH Range
5	pH Stability
6	pI Value
11	Posttranslational Modification
105	Protein Variants
51	Purification (Commentary)
3	Reaction
1	Reaction Type
175	Reference
1	Renatured (Commentary)
123	Source Tissue
61	Specific Activity [micromol/min/mg]
11	Storage Stability
373	Substrates and Products (Substrate)
47	Subunits
97	Synonyms
1	Systematic Name
36	Temperature Optimum [°C]
5	Temperature Range [°C]
28	Temperature Stability [°C]
93	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 3.1.1.2 - arylesterase

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aryl-ester hydrolase

Acts on many phenolic esters. The reactions of EC 3.1.8.1 aryldialkylphosphatase, were previously attributed to this enzyme. It is likely that the three forms of human paraoxonase are lactonases rather than aromatic esterases [7,8]. The natural substrates of the paraoxonases are lactones [7,8], with (+/-)-5-hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best substrate [8].