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3.1.1.1: carboxylesterase

This is an abbreviated version!
For detailed information about carboxylesterase, go to the full flat file.

Word Map on EC 3.1.1.1

Reaction

a carboxylic ester
+
H2O
=
an alcohol
+
a carboxylate

Synonyms

4-nitrophenyl esterase, ACAT, Acetyl esterase, acetyl xylan esterase, acid retinyl ester hydrolase, AcXE, Acyl coenzyme A:cholesterol acyltransferase, acylcarnitine hydrolase, AF1716, AF1763, AFEST, ali-esterase, aliesterase, alpha-carboxylesterase, alpha-esterase 7, alphaE7, alphaEsterase7, AOPP herbicide carboxylesterase, APE1547, AREH, aspirin hydrolase, Axe1NaM1, Axe1NaM2, Axe1NaM3, B-esterase, Bacillus esterase, BdB1, BioHe, BioHs, Brain carboxylesterase hBr1, BSE, BsE-NP01, BSE01701, butyrate esterase, butyryl esterase, CaE, CaesCCR11, carboxyesterase, Carboxyesterase ES-10, carboxyl ester hydrolase, carboxyl esterase, carboxyl/cholinesterase, carboxylate esterase, carboxylesterase, carboxylesterase 1, carboxylesterase 1A2, carboxylesterase 1C, carboxylesterase 2, carboxylesterase B, carboxylesterase B1, carboxylesterase-1, carboxylesterase-2, Carboxylesterase-5C, carboxylic acid esterase, carboxylic ester hydrolase, carboxylic esterase, Carboxylic-ester hydrolase, CarE, CbE, CCE, CE, CE-1, CE-2, CE1, CE2, CE21p, CE7 AcXE, CEH, CES, CES 1C, CES-2, CES1, CES1-b, CES1-c, CES1A, CES1A1, CES1A2, Ces1c, Ces1d, Ces1e, Ces1g, CES2, CES2A1, Ces3-1, Ces3a, cholesteryl ester hydrolase, cocaine esterase, cocaine:benzoylecgonine esterase, COE, CPT-CE, CXE, CXE1, CXE10, D1CarE5, de-arenethiolase, DEHP, E3 carboxylesterase, E34Tt, EC 3.1.1.21, Egasyn, ES-10, Es-22, ES-HTEL, ES-HVEL, ES-Male, ES-THET, ES10, ES11, ES3, ES4, ES5, ES6, ES7, ES9, EST, EST-3, EST-4, EST-5A, EST-5B, EST-5C, Est-AF, Est0071, Est1, Est1C, EST2, ESt3, Est3 esterase, Est30, Est55, EstA, EstA esterase, EstB, estBB1, EstC, EstC1, esterase, esterase 1F, esterase 2, esterase 2B, esterase 6A, esterase 9A, esterase A, esterase B, esterase B1, esterase D, esterase Sso2518, esterase, carboxyl, Esterase-22, Esterase-31, esterase-6, EStFa, EstGtA2, EstP, EstPS1, EstSt7, EstU1, Fluazifop-P-butyl carboxylesterase, Fluazifop-P-butyl hydrolase, FpbH, fungus-inducible pepper carboxylesterase, general odorant degradation enzyme, GODE, hCE-2, HCE1, HCE2, hCES1, hiCE, HMSE, hormone-sensitive lipase, HSL, human carboxylesterase 1, human carboxylesterase 2, human liver carboxylesterase, ICE, ICXE14, JHE-related, JHER, kidney bean esterase, Kidney microsomal carboxylesterase, LcalphaE7, LIP4, LipA, LipC, Liver microsomal carboxylesterase, malathion carboxylesterase, MAP esterase, MCE, ME, MeIAA esterase, MeSA esterase, methylbutyrase, methylbutyrate esterase, mfCES2v3, Microsomal palmitoyl-CoA hydrolase, monobutyrase, Monocyte/macrophage serine esterase, More, mouse carboxylesterase, MT2282, NaM1, NaM2, NaM3, Non-specific carboxylesterase, nonspecific carboxylesterase, ODE, odorant degradation enzyme, P186_1588, PA3859, PepEST, PF2001, Pf2001 esterase, PI 5.5 esterase, PI 6.1 esterase, pig liver esterase, PLE, PMPMEase, pnbA, PnbA1, PnbA2, polyisoprenylated methylated protein methyl esterase, porcine liver carboxylesterase, PPE, PPMTase, PrbA, prenylated methylated protein methyl esterase, procaine esterase, Proline-beta-naphthylamidase, propionyl esterase, pyrethroid-hydrolysing esterase, Rsp3690, SABP2's methyl salicylate esterase, salicylic acid-binding protein 2, SeE, serine protease-like, serine-type carboxylesterase, SexiCXE10, SiRe0290, SshEstI, SshEstI esterase, Sso P1 carboxylesterase, Sso-EST1, SSO2493, SSO2517, SSoP1 CE, SsoPEst, ST0071, ST2026, STK_00710, Sto-Est, TGH, triacetin esterase, triacylglycerol hydrolase, vitamin A esterase, VmoLac

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.1 carboxylesterase

Molecular Weight

Molecular Weight on EC 3.1.1.1 - carboxylesterase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
114000
-
gel filtration
117000
meniscus depletion sedimentation equilibrium in the analytical ultracentrifuge
120000
125000
gel filtration
135000 - 140000
-
gel filtration
144500
-
gel filtration
160000
-
esterase II, gel filtration
16700
-
nondenaturing PAGE
170000
-
gel filtration
174000
-
isoenzyme pI 6.0, gel filtration
175000
176000
-
gel filtration
177000
-
equilibrium sedimentation
180000
-
liver enzyme, trimeric form, gel filtration in 50 mM Tris-HCl, pH 7.5, 200 mM KCl
181000 - 186000
-
gel filtration, disc electrophoresis, analytical ultracentrifugation
182000
-
gel filtration
184000
-
gel filtration
19300
19500
-
gel filtration
195000
-
gel filtration
20000
-
1 * 20000, SDS-PAGE
200000
-
gel filtration
206000
-
gel filtration
209000
-
trimeric enzyme form, gel filtration
21130
calculated from sequence
216000
-
recombinant wild-type enzyme, gel filtration
22000
-
x * 22000, SDS-PAGE
24000
24691
-
1 * 28000, SDS-PAGE, 1 * 24691, ESI-MS
26000
-
x * 26000, SDS-PAGE
260000
27000
-
2 * 27000, SDS-PAGE, both E1 and E2
27500
-
gel filtration
27528
-
x * 27528, calculated
28000
28300
x * 28300, SDS-PAGE
28338
-
Est30, 2 * 28338, calculated
29000
29152
x * 29152, mass spectrometry
30000
300000
recombinant enzyme, gel filtration
31700
-
x * 31700, calculated
32000
33000
33425
-
4 * 33425, calculated from sequence
33428
3 * 33428, calculated from sequence
33800
1 * 33800, SDS-PAGE
33810
x * 33810, calculated from sequence
34000
340000
-
gel filtration
34260
1 * 34260, calculated from sequence
34354
3 * 34354, calculation from sequence
34734
1 * 34734, calculated from sequence
35000
35500
x * 35500, SDS-PAGE
36000
1 * 36000, SDS-PAGE
36445
calculated from sequence
36500
-
1 * 36500, SDS-PAGE
36600
-
x * 36600, SDS-PAGE
37000
37400
x * 37400, calculated from sequence
37500
-
gel filtration
38000
-
gel filtration
39313
-
x * 40000, SDS-PAGE, x * 39313, calculated, His-tagged protein
39800
-
x * 39800, predicted molecular mass for the N-terminal His6-tagged version of CXE1
40000
40000 - 45000
recombinant enzyme, gel filtration
40400
3 * 40400, calculated from sequence
41000
42000
42100
43000
43300
-
x * 42000, SDS-PAGE, x * 43300, calculated, His-tagged protein
44000
45000
46000
-
Est55, gel filtration
49000
-
analytical ultracentrifugation
50000
51000
-
gel filtration
52000
52800
54300
-
gel filtration
54620
-
mass spectrometry
54867
-
Est55, 1 * 54867, calculated
55000
-
Est30, gel filtration
56000
57000
57100
-
1 * 57100, SDS-PAGE
57820
x * 57820, calculated from amino acid sequence
58000
58400
x * 58400, SDS-PAGE
59000
-
3 * 59000, SDS-PAGE
600000
-
gel filtration
60200
-
3 * 60200, SDS-PAGE
61000
61500
61700
-
malathion carboxylesterase, gel filtration
62000
63000
64000
64240
-
x * 64240, calculated from amino acid sequence
65000
65300
-
1 * 65300, SDS-PAGE
66000
x * 66000, SDS-PAGE
67000
67064
x * 67500, SDS-PAGE, x * 67064, calculated, protein with S-tag
67200
-
x * 67200, SDS-PAGE
67500
x * 67500, SDS-PAGE, x * 67064, calculated, protein with S-tag
69000
70000
-
esterase I, gel filtration
70800
-
3 * 70800, SDS-PAGE
71800
gel filtration
72000
72800
-
1 * 72800, SDS-PAGE
72900
-
gel filtration
73000
gel filtration
73500
1 * 73000, SDS-PAGE, 1 * 73500, calculated
75000
-
x * 75000, SDS-PAGE
76000
-
gel filtration
80000
84000
-
gel filtration
85000
-
4 * 85000, SDS-PAGE
90000
-
trimer, gel filtration
94000
-
gel filtration
95000
98000
gel filtration