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2.1.1.115: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase

This is an abbreviated version!
For detailed information about (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline
=
S-adenosyl-L-homocysteine
+
N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline

Synonyms

Norreticuline N-methyltransferase, Methyltransferase, tetrahydrobenzylisoquinoline, (R,S)-Tetrahydrobenzylisoquinoline-N-methyltransferase, NMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase

Application

Application on EC 2.1.1.115 - (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
Berberis koetineana
-
the enzyme immobilized on CH-Sepharose or CPG-10 glass beads is a useful tool for the preparative synthesis of isotopically labelled N-methylated benzylisoquinoline alkaloids