Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.97.1.4: [formate-C-acetyltransferase]-activating enzyme

This is an abbreviated version!
For detailed information about [formate-C-acetyltransferase]-activating enzyme, go to the full flat file.

Word Map on EC 1.97.1.4

Reaction

S-adenosyl-L-methionine
+
dihydroflavodoxin
+
[formate C-acetyltransferase]-glycine
=
5'-deoxyadenosine
+
L-methionine
+
flavodoxin semiquinone
+
[formate C-acetyltransferase]-glycin-2-yl radical
+
H+

Synonyms

PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving), Activase, pyruvate formate-lyase, Formate acetyltransferase activase, Pyruvate formate-lyase activase, Pyruvate formate-lyase activating enzyme, PFL-AE, Formate-lyase-activating enzyme, PFL activase, PFL-activating enzyme, PFL, pyruvate formate lyase activating enzyme, PFL activating enzyme, pyruvate formate-lyase-activating enzyme, PflA

ECTree

     1 Oxidoreductases
         1.97 Other oxidoreductases
             1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
                1.97.1.4 [formate-C-acetyltransferase]-activating enzyme

Systematic Name

Systematic Name on EC 1.97.1.4 - [formate-C-acetyltransferase]-activating enzyme

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
[formate C-acetyltransferase]-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)
An iron-sulfur protein. A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase, is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5'-yl radical, which then abstracts a hydrogen radical from the glycine residue.