1.97.1.4: [formate-C-acetyltransferase]-activating enzyme

This is an abbreviated version!
For detailed information about [formate-C-acetyltransferase]-activating enzyme, go to the full flat file.

Reaction

Synonyms

Activase, pyruvate formate-lyase, Formate acetyltransferase activase, Formate-lyase-activating enzyme, PFL, PFL activase, PFL activating enzyme, PFL-activating enzyme, PFL-AE, PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving), PflA, pyruvate formate lyase activating enzyme, Pyruvate formate-lyase activase, Pyruvate formate-lyase activating enzyme, pyruvate formate-lyase-activating enzyme

ECTree

     1 Oxidoreductases

         1.97 Other oxidoreductases

             1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses

                1.97.1.4 [formate-C-acetyltransferase]-activating enzyme

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	Activating Compound
11817	AA Sequence
1	Application
1	CAS Registry Number
9	Cloned(Commentary)
8	Cofactor
1	Crystallization (Commentary)
1	Expression
10	General Information
4	Inhibitors
3	KM Value [mM]
3	Localization
14	Metals/Ions
8	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
27	Organism
2	PDB ID
4	pH Optimum
1	pI Value
10	Protein Variants
5	Purification (Commentary)
4	Reaction
2	Reaction Type
26	Reference
1	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
29	Substrates and Products (Substrate)
5	Subunits
27	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.97.1.4 - [formate-C-acetyltransferase]-activating enzyme

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

[formate C-acetyltransferase]-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)

An iron-sulfur protein. A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase, is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5'-yl radical, which then abstracts a hydrogen radical from the glycine residue.