1.8.5.8: eukaryotic sulfide quinone oxidoreductase

This is an abbreviated version!
For detailed information about eukaryotic sulfide quinone oxidoreductase, go to the full flat file.

Reaction

Synonyms

glutathione:CoQ reductase, HMT2, ScSQR, SQOR, SQR, Sqrdl, sulfide : quinone oxidoreductase, sulfide quinone oxidoreductase, sulfide:quinone oxidoreductase

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.5 With a quinone or similar compound as acceptor

1.8.5.8 eukaryotic sulfide quinone oxidoreductase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
2	Activating Compound
11	AA Sequence
3	Application
6	Cloned(Commentary)
17	Cofactor
3	Crystallization (Commentary)
2	Expression
27	General Information
1	General Stability
5	IC50 Value
22	Inhibitors
15	kcat/KM [mM/s]
4	Ki Value [mM]
22	KM Value [mM]
17	Localization
13	Natural Substrates/ Products (Substrates)
19	Organism
4	Pathway
2	pH Optimum
1	pH Range
1	pI Value
2	Posttranslational Modification
2	Protein Variants
6	Purification (Commentary)
5	Reaction
19	Reference
18	Source Tissue
1	Specific Activity [micromol/min/mg]
44	Substrates and Products (Substrate)
6	Subunits
43	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
11	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.8.5.8 - eukaryotic sulfide quinone oxidoreductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Systematic Name Search

sulfide:glutathione,quinone oxidoreductase

Contains FAD. This eukaryotic enzyme, located at the inner mitochondrial membrane, catalyses the first step in the metabolism of sulfide. While both sulfite and glutathione have been shown to act as sulfane sulfur acceptors in vitro, it is thought that the latter acts as the main acceptor in vivo. The electrons are transferred via FAD and quinones to the electron transfer chain. Unlike the bacterial homolog (EC 1.8.5.4, bacterial sulfide:quinone reductase), which repeats the catalytic cycle without releasing the product, producing a polysulfide, the eukaryotic enzyme transfers the persulfide to an acceptor at the end of each catalytic cycle.