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1.8.5.7: glutathionyl-hydroquinone reductase

This is an abbreviated version!
For detailed information about glutathionyl-hydroquinone reductase, go to the full flat file.

Reaction

glutathione
+
2-(glutathione-S-yl)-hydroquinone
=
glutathione disulfide
+
hydroquinone

Synonyms

ECM4, GHR1, glutathionyl-hydroquinone lyase, glutathionyl-hydroquinone reductase, nmagghr, Nmag_1170, NmGHR, pcpF, Xi class glutathione transferase, Xi class GST, yqjG

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.5 With a quinone or similar compound as acceptor
                1.8.5.7 glutathionyl-hydroquinone reductase

Engineering

Engineering on EC 1.8.5.7 - glutathionyl-hydroquinone reductase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C63A
catalytic residue, mutant displays negligible activity
Y195F
catalytic residue, mutant displays negligible activity
Y253F
catalytic residue, mutant displays negligible activity
Y296F
catalytic residue, mutant displays negligible activity
C49A
-
mutation of catalytic cysteine, loss of activity
C49S
-
mutation of catalytic cysteine, loss of activity