1.8.5.4: bacterial sulfide:quinone reductase

This is an abbreviated version!
For detailed information about bacterial sulfide:quinone reductase, go to the full flat file.

Reaction

n HS- + n quinone =

Synonyms

CmSQR, CpSQR, CT1087, HMT2, III SQR, membrane-bound sulfide:quinone oxidoreductases, SQOR, SQR, Sqrdl, sqrF, Suden_1879, Suden_2082, Suden_619, sulfide quinone oxidoreductase, sulfide quinone reductase, sulfide-quinone oxidoreductase, sulfide-quinone reductase, sulfide: quinone oxidoreductase, sulfide:decylubiquinone oxidoreductase, sulfide:quinone oxidoreductase, sulfidequinone reductase-like protein, TrSqrF, type I SQR, type III sulfide:quinone oxidoreductase, type VI sulfide:quinone oxidoreductase

ECTree

     1 Oxidoreductases

         1.8 Acting on a sulfur group of donors

             1.8.5 With a quinone or similar compound as acceptor

                1.8.5.4 bacterial sulfide:quinone reductase

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Results	in table
4	Activating Compound
131	AA Sequence
2	Application
25	Cloned(Commentary)
38	Cofactor
7	Crystallization (Commentary)
24	Disease/ Diagnostics
4	Expression
37	General Information
31	IC50 Value
45	Inhibitors
36	kcat/KM [mM/s]
1	Ki Value [mM]
86	KM Value [mM]
40	Localization
21	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
64	Organism
4	Pathway
16	pH Optimum
3	pH Range
4	pI Value
64	Protein Variants
22	Purification (Commentary)
2	Reaction
4	Reaction Type
60	Reference
34	Source Tissue
18	Specific Activity [micromol/min/mg]
3	Storage Stability
100	Substrates and Products (Substrate)
23	Subunits
118	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
2	Temperature Range [°C]
5	Temperature Stability [°C]
50	Turnover Number [1/s]

Disease

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Disease on EC 1.8.5.4 - bacterial sulfide:quinone reductase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Heart Failure

Discovery of a first-in-class inhibitor of sulfide:quinone oxidoreductase that protects against adverse cardiac remodeling and heart failure.

34132787

Leigh Disease

Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease.

32160317

Metabolic Syndrome

Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet.

20332082

Osteoporosis

Association of the I264T variant in the sulfide quinone reductase-like (SQRDL) gene with osteoporosis in Korean postmenopausal women.

26258864

Osteoporosis

Genetic susceptibility of postmenopausal osteoporosis on sulfide quinone reductase-like gene.

29855663

Osteoporosis, Postmenopausal

Association of the I264T variant in the sulfide quinone reductase-like (SQRDL) gene with osteoporosis in Korean postmenopausal women.

26258864

Osteoporosis, Postmenopausal

Genetic susceptibility of postmenopausal osteoporosis on sulfide quinone reductase-like gene.

29855663

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