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1.8.4.8: phosphoadenylyl-sulfate reductase (thioredoxin)

This is an abbreviated version!
For detailed information about phosphoadenylyl-sulfate reductase (thioredoxin), go to the full flat file.

Word Map on EC 1.8.4.8

Reaction

adenosine 3',5'-bisphosphate
+
sulfite
+
thioredoxin disulfide
=
3'-phosphoadenylyl sulfate
+
thioredoxin

Synonyms

3'-Phosphoadenosine 5'-phosphosulfate reductase, 3'-Phosphoadenylylsulfate reductase, 4Fe-4S adenylyl sulfate/phosphoadenylyl sulfate reductase, 5'-adenylylsulfate reductase, Adenosine 3'-phosphate 5'-phosphosulfate reductase, adenosine 5'-phosphosulfate reductase, Adenylyl phosphosulfate reductase, APR, APS reductase, CysH1, EC 1.8.99.4, PAdoPS reductase, PAPS reductase, PAPS reductase, thioredoxin dependent, PAPS reductase, thioredoxin-dependent, PAPS sulfotransferase, Phospho-adenylylsulfate (PAPS) reductase, Phospho-adenylylsulfate reductase, Reductase, 3'-phosphoadenosine 5'-phosphosulfate, SNR, Thioredoxin: 3'-phospho-adenylylsulfate reductase, Thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin)

KM Value

KM Value on EC 1.8.4.8 - phosphoadenylyl-sulfate reductase (thioredoxin)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0287 - 0.1054
3'-phosphoadenylyl sulfate
0.0064 - 0.0225
3'-phosphoadenylyl-sulfate
0.01 - 0.021
5-Phosphoadenosine 3-phosphosulfate
0.0149 - 0.0606
glutaredoxin 1
-
0.0637
glutaredoxin Grx
-
pH 8.0, temperature not specified in the publication
-
0.0149
glutaredoxin Grx1
-
pH 8.0, temperature not specified in the publication
-
0.0072
glutaredoxin mutant 1C14S
-
pH 8.0
-
0.023
reduced thioredoxin
-
-
0.0006 - 0.0014
thioredoxin
0.0137 - 0.0675
thioredoxin 1
0.0342
thioredoxin 2
-
pH 8.0
-
0.0681
thioredoxin hTrx1
-
pH 8.0, temperature not specified in the publication
-
0.01
thioredoxin I
-
wild type enzyme, at 20°C in 10 mM phosphate buffer (pH 7.5) containing 100 mM Na2SO4
0.0137
thioredoxin Trx1
-
pH 8.0, temperature not specified in the publication
-
0.0342
thioredoxin Trx2
-
pH 8.0, temperature not specified in the publication
-
0.059
thioredoxin TrxH1
-
pH 8.0, temperature not specified in the publication
-
0.0431
thioredoxin TrxH2
-
pH 8.0, temperature not specified in the publication
-
0.0178
thioredoxin TrxH3
-
pH 8.0, temperature not specified in the publication
-
0.0261
thioredoxin TrxH4
-
pH 8.0, temperature not specified in the publication
-
additional information
additional information
-
kinetics
-