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1.8.4.13: L-methionine (S)-S-oxide reductase

This is an abbreviated version!
For detailed information about L-methionine (S)-S-oxide reductase, go to the full flat file.

Reaction

L-methionine
+
thioredoxin disulfide
+
H2O
=
L-methionine (S)-S-oxide
+
thioredoxin

Synonyms

EC 1.8.4.5, free-methionine-R-sulfoxide reductase, fRMsr, fSMsr, methionine sulfoxide reductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.13 L-methionine (S)-S-oxide reductase

Inhibitors

Inhibitors on EC 1.8.4.13 - L-methionine (S)-S-oxide reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-chloromercuribenzoate
-
complete inhibition at 1 mM
arsenite
-
strong inhibition
bovine serum albumin
-
-
-
DL-methionine sulfoximine
-
50% inhibition at 1 mM
hydroxyethyl disulfide
-
competitively inhibits the activity with L-(-)-methionine S-oxide about 2.5fold
iodoacetic acid
-
complete inhibition at 10 mM
L-(-)-methionine S-oxide
-
competitively inhibits the activity with a disulfide about 2.5fold