1.8.3.7: formylglycine-generating enzyme
This is an abbreviated version!
For detailed information about formylglycine-generating enzyme, go to the full flat file.
Word Map on EC 1.8.3.7
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1.8.3.7
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sulfatases
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metachromatic
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mucopolysaccharidosis
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leukodystrophy
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ichthyosis
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antibody-drug
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ultra-rare
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morquio
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medicine
- 1.8.3.7
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sulfatases
-
metachromatic
- mucopolysaccharidosis
- leukodystrophy
-
ichthyosis
-
antibody-drug
-
ultra-rare
- morquio
- medicine
Reaction
Synonyms
AtsB, C-alpha-formylglycine-generating enzyme 1, Calpha-formylglycine-generating enzyme, Calpha-formylglycine-generating enzyme 1, FGE, FGly-generating enzyme, formylglycine generating enzyme, sulfatase-modifying factor 1, SUMF1
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KCat KM Value
KCat KM Value on EC 1.8.3.7 - formylglycine-generating enzyme
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0.000317
pH 8.0, 25掳C, mutant enzyme W228F
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0.00082
Abz-ATTPLCGPSRASILSGR
pH 8.0, 25掳C, mutant enzyme S266A
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0.00011
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mutant S290K, at pH 8.0, temperature not specified in the publication
0.00082
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant S266A, at pH 8.0, temperature not specified in the publication
0.048
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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wild type enzyme, at pH 8.0, temperature not specified in the publication
0.0483
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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wild type enzyme, at pH 8.0 and 25掳C
0.233
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant C187A/C284S/C298A, at pH 8.0 and 25掳C
0.316
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant Y273F, at pH 8.0 and 25掳C
0.333
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant C187A/C231A/C284S/C298A, at pH 8.0 and 25掳C
0.333
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant C187A/C231A/C284S/C298A, at pH 8.0, temperature not specified in the publication
1.833
Abz-SAL-3-oxo-L-Ala-SPTRA-NH2
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mutant C187A/C231A/Y273F/C284S/C298A, at pH 8.0 and 25掳C
0.0101
mutant enzyme S290K, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.005 mM CuSO4, pH 8.0
0.333
Abz-SALCSPTRA-NH2
mutant enzyme C187A/C231A/C284S/C298A, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.005 mM CuSO4, pH 8.0
1.7
Abz-SALCSPTRA-NH2
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wild-type enzyme, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, pH 8.0
8.17
Abz-SALCSPTRA-NH2
mutant enzyme S266A, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.005 mM CuSO4, pH 8.0
17
Abz-SALCSPTRA-NH2
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mutant enzyme C187A/C231A/C284S/C298A, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, pH 8.0
48.3
Abz-SALCSPTRA-NH2
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wild-type enzyme, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.002 mM CuSO4, pH 8.0
48.33
Abz-SALCSPTRA-NH2
wild-type enzyme, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.005 mM CuSO4, pH 8.0
333.3
Abz-SALCSPTRA-NH2
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mutant enzyme C187A/C231A/C284S/C298A, 25掳C, 5 mM DTT, 50 mM EDTA, 50 mM NaCl, and 50 mM Tris路HCl, 0.002 mM CuSO4, pH 8.0