1.8.1.8: protein-disulfide reductase

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For detailed information about protein-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.8

1.8.1.8

thioredoxins

gsh

monothiol

ribonucleotide

peroxiredoxins

deglutathionylation

glutathione-dependent

redox-active

reductases

thiol-disulfide

iron-sulfur

fe-s

redox-sensitive

thioltransferase

trx1

thioredoxin-like

dehydroascorbate

nadph-dependent

cys

hydroperoxide

deoxyribonucleotides

selenoenzyme

auranofin

bola

thioredoxin-dependent

redox-dependent

selenocysteine

gsh-dependent

trypanothione

thiol-based

diamide

oxidoreduction

dtnb

peroxidases

redox-regulated

sulfenic

dsba

ask1

poplar

selenoproteins

sideroblast

thiol-dependent

Reaction

Synonyms

AhpF, disulfide reductase, EC 1.6.4.4, ERdj5, ERp16, glutaredoxin, HvTrxh2, insulin-glutathione transhydrogenase, LpdA, MA3736, MA_1658, MdrA, methanoredoxin, More, NAD(P)H:protein-disulfide oxidoreductase, NADH-linked disulfide reductase, panthethine 4'4-diphosphate-specific reductase, PDI reductase, PDO, PfPDO, PH1130 protein, PhDsb, protein disulfide isomerase reductase, protein disulfide oxidoreductase, protein disulfide reductase, protein-disulfide oxidoreductase, protein-disulfide reductase (NAD(P)H), reductase, protein disulfide, thiol-disulfide oxidoreductase, TON_0319, TTC0486, WhiB1, WhiB1/Rv3219

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.1 With NAD⁺ or NADP⁺ as acceptor

1.8.1.8 protein-disulfide reductase

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Results	in table
14437	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
21	Cofactor
6	Crystallization (Commentary)
363	Disease/ Diagnostics
1	General Information
2	General Stability
13	Inhibitors
2	Ki Value [mM]
17	KM Value [mM]
1	Localization
2	Metals/Ions
11	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
35	Organism
82	PDB ID
4	pH Optimum
2	pH Range
4	pH Stability
3	pI Value
1	Protein Variants
10	Purification (Commentary)
2	Reaction
8	Reaction Type
34	Reference
17	Source Tissue
2	Specific Activity [micromol/min/mg]
7	Storage Stability
53	Substrates and Products (Substrate)
17	Subunits
56	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
6	Temperature Stability [°C]
12	Turnover Number [1/s]

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Turnover Number on EC 1.8.1.8 - protein-disulfide reductase

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0.0077 - 2.8

2,6-dimethyl-1,4-benzoquinone

2 entries

0.0079 - 2.5

5-hydroxy-1,4-naphthoquinone

2 entries

0.0087

NAD(P)H

Mycobacterium tuberculosis

pH 7.5, 25°C, with thio-NAD+

659424

2.5 - 3.6

NADH

3 entries

0.0077 - 0.0079

NADPH

2 entries

0.0087 - 3.6

thio-NAD+

2 entries