1.8.1.8: protein-disulfide reductase

This is an abbreviated version!
For detailed information about protein-disulfide reductase, go to the full flat file.

Reaction

Synonyms

AhpF, disulfide reductase, EC 1.6.4.4, ERdj5, ERp16, glutaredoxin, HvTrxh2, insulin-glutathione transhydrogenase, LpdA, MA3736, MA_1658, MdrA, methanoredoxin, More, NAD(P)H:protein-disulfide oxidoreductase, NADH-linked disulfide reductase, panthethine 4'4-diphosphate-specific reductase, PDI reductase, PDO, PfPDO, PH1130 protein, PhDsb, protein disulfide isomerase reductase, protein disulfide oxidoreductase, protein disulfide reductase, protein-disulfide oxidoreductase, protein-disulfide reductase (NAD(P)H), reductase, protein disulfide, thiol-disulfide oxidoreductase, TON_0319, TTC0486, WhiB1, WhiB1/Rv3219

ECTree

     1 Oxidoreductases

         1.8 Acting on a sulfur group of donors

             1.8.1 With NAD⁺ or NADP⁺ as acceptor

                1.8.1.8 protein-disulfide reductase

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Results	in table
14437	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
21	Cofactor
6	Crystallization (Commentary)
363	Disease/ Diagnostics
1	General Information
2	General Stability
13	Inhibitors
2	Ki Value [mM]
17	KM Value [mM]
1	Localization
2	Metals/Ions
11	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
35	Organism
82	PDB ID
4	pH Optimum
2	pH Range
4	pH Stability
3	pI Value
1	Protein Variants
10	Purification (Commentary)
2	Reaction
8	Reaction Type
34	Reference
17	Source Tissue
2	Specific Activity [micromol/min/mg]
7	Storage Stability
53	Substrates and Products (Substrate)
17	Subunits
56	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
6	Temperature Stability [°C]
12	Turnover Number [1/s]

Synonyms

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Synonyms on EC 1.8.1.8 - protein-disulfide reductase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

AhpF

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

657677

disulfide reductase

3 entries

EC 1.6.4.4

-

-

formerly

-

ERdj5

Mus musculus

Q9DC23

-

725973

ERp16

Homo sapiens

-

-

687756

glutaredoxin

2 entries

HvTrxh2

Hordeum vulgare

-

-

677156

insulin-glutathione transhydrogenase

-

-

-

-

LpdA

Mycobacterium tuberculosis

-

-

659424

MA3736

Methanosarcina acetivorans

-

-

687393

MA_1658

2 entries

MdrA

Methanosarcina acetivorans

-

-

687393

methanoredoxin

2 entries

NAD(P)H:protein-disulfide oxidoreductase

-

-

-

-

NADH-linked disulfide reductase

Priestia megaterium

-

-

680424, 680588

panthethine 4'4-diphosphate-specific reductase

Priestia megaterium

-

-

680424

PDI reductase

Homo sapiens

-

-

671296

PDO

5 entries

PfPDO

Pyrococcus furiosus

-

-

745638

PH1130 protein

2 entries

PhDsb

2 entries

protein disulfide isomerase reductase

Homo sapiens

-

-

671296

protein disulfide oxidoreductase

5 entries

protein disulfide reductase

4 entries

protein-disulfide oxidoreductase

2 entries

protein-disulfide reductase (NAD(P)H)

-

-

-

-

reductase, protein disulfide

-

-

-

-

thiol-disulfide oxidoreductase

Homo sapiens

-

-

687756

TON_0319

Thermococcus onnurineus

B6YTB7

-

742471

TTC0486

2 entries

WhiB1

2 entries

WhiB1/Rv3219

2 entries

additional information

Mycobacterium tuberculosis

-

enzyme is a member of the flavoprotein disulfide reductase family of enzymes

659424

disulfide reductase

-

-

-

-

disulfide reductase

Homo sapiens

-

-

671296

disulfide reductase

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

657677

glutaredoxin

Methanosarcina acetivorans

Q8TQ93

-

741927

glutaredoxin

Methanosarcina acetivorans DSM 2834

Q8TQ93

-

-

MA_1658

Methanosarcina acetivorans

Q8TQ93

-

741927

MA_1658

Methanosarcina acetivorans DSM 2834

Q8TQ93

-

-

methanoredoxin

Methanosarcina acetivorans

Q8TQ93

-

741927

methanoredoxin

Methanosarcina acetivorans DSM 2834

Q8TQ93

-

-

PDO

Pyrococcus furiosus

-

-

673557

PDO

Pyrococcus horikoshii

-

-

673557

PDO

Saccharolobus solfataricus

-

-

673557

PDO

Thermococcus kodakarensis

-

-

673557

PDO

Thermotoga maritima

-

-

673557

PH1130 protein

Pyrococcus horikoshii

O58857

-

722206

PH1130 protein

Pyrococcus horikoshii OT-3

O58857

-

-

PhDsb

Pyrococcus horikoshii

O58857

-

722206

PhDsb

Pyrococcus horikoshii OT-3

O58857

-

-

protein disulfide oxidoreductase

Pyrococcus furiosus

-

-

673557

protein disulfide oxidoreductase

Pyrococcus horikoshii

-

-

673557

protein disulfide oxidoreductase

Saccharolobus solfataricus

-

-

673557

protein disulfide oxidoreductase

Thermococcus kodakarensis

-

-

673557

protein disulfide oxidoreductase

Thermotoga maritima

-

-

673557

protein disulfide reductase

-

-

-

-

protein disulfide reductase

Mus musculus

Q9DC23

-

725973

protein disulfide reductase

Mycobacterium tuberculosis

-

-

670797

protein disulfide reductase

Mycobacterium tuberculosis Rv3219

-

-

-

protein-disulfide oxidoreductase

Pyrococcus horikoshii

O58857

-

722206

protein-disulfide oxidoreductase

Pyrococcus horikoshii OT-3

O58857

-

-

TTC0486

Thermus thermophilus

Q72KI9

-

742467

TTC0486

Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039

Q72KI9

-

-

WhiB1

Mycobacterium tuberculosis

-

wild type enzyme

670797

WhiB1

Mycobacterium tuberculosis Rv3219

-

wild type enzyme

-

WhiB1/Rv3219

Mycobacterium tuberculosis

-

recombinant enzyme

670797

WhiB1/Rv3219

Mycobacterium tuberculosis Rv3219

-

recombinant enzyme

-