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1.8.1.7: glutathione-disulfide reductase

This is an abbreviated version!
For detailed information about glutathione-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.7

Reaction

2 glutathione +

NADP+
=
glutathione disulfide
 +
NADPH
 +
H+

Synonyms

At3g54660, EC 1.6.4.2, GLR, glutahione reductase, glutathione disulfide reductase, glutathione reductase, glutathione reductase (NADPH), glutathione reductase 3, glutathione reductase Glr1, glutathione S-reductase, glutathione: NADP(+) oxidoreductase, glutathione: NADP+ oxidoreductase, glutathione:NADP+ oxidoreductase, Gor, GOR1, GOR2, GR, GR1, GR2, Gr3, GRase, GRase-1, GRd, GSH reductase, GSHR, Gsr, GSR-1, GSSG reductase, HCOI_01258400, hGR, HvGR1, HvGR2, multifunctional thioredoxin-glutathione reductase, NADPH-glutathione reductase, NADPH-GSSG reductase, NADPH-reduced GR, NADPH: oxidized glutathione oxidoreductase, NADPH:oxidized glutathione oxidoreductase, NADPH:oxidized-glutathione oxidoreductase, OBP29, PfGR, psgr, PtGR1.1, PtGR1.2, PtGR2, reductase, glutathione, SpGR, TaGR1, TaGR2, TGR, thioredoxin glutathione reductase, thioredoxin/glutathione reductase, TrxR3

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.7 glutathione-disulfide reductase

KCat KM Value

KCat KM Value on EC 1.8.1.7 - glutathione-disulfide reductase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.2
1,4-dihydroxy-9,10-anthraquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
5.2
1,4-Naphthoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.4
1,8-dihydroxy-9,10-anthraquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.1
2,5-bis(aziridin-1-yl)-3,6-dimethylcyclohexa-2,5-diene-1,4-dione
-
kcat_Km above 0.1 1/sec*mM, pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.25
2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione
-
kcat_Km above 0.25 1/sec*mM, pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
40
2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
6.5
2,6-dimethyl-1,4-benzoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
1.8
2-methyl-1,4-naphthoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
430
5,8-Dihydroxy-1,4-naphthoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
360
5-hydroxy-1,4-naphthoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
4.2
9,10-phenanthrene quinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.8
diethyl [2,5-bis(aziridin-1-yl)-3,6-dioxocyclohexa-1,4-diene-1,4-diyl]biscarbamate
-
kcat_Km above 0.8 1/sec*mM, pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
2.95 - 5790
glutathione disulfide
46.7 - 16800
NADPH
1
tetramethyl-1,4-benzoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.7
trimethyl-1,4-benzoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C
0.65
trimethyl-aziridinyl-1,4-benzoquinone
-
pH 7.0, 0.1 M potassium phosphate, 1 mM EDTA, 25°C