1.8.1.6: cystine reductase

This is an abbreviated version!
For detailed information about cystine reductase, go to the full flat file.

Word Map on EC 1.8.1.6

Reaction

2 L-cysteine +

NAD+
=
L-cystine
+
NADH
+
H+

Synonyms

CysR, cystine reductase (NADH), cystine reductase (NADH2), EC 1.6.4.1, L-cysteine:NAD+ oxidoreductase, L-cystine reductase, NADH-dependent cystine reductase, NADH2:L-cystine oxidoreductase, reductase, cystine, thioredoxin domain containing 17, thioredoxin-like 5, TRP14, TXNDC17, TXNL5

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.6 cystine reductase

Disease

Disease on EC 1.8.1.6 - cystine reductase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Bone Resorption
TRP14 inhibits osteoclast differentiation via its catalytic activity.
Colorectal Neoplasms
Retraction notice to "STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells" [GENE 584 (1) (2016) 75-82].
STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells.
Decompression Sickness
Dynorphin-phospholipid membrane interactions: role of phospholipid head-group and cholesterol.
Neoplasms
Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.
Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin-related protein 14-mediated autophagy.
Thioredoxin-related protein 14, a new member of the thioredoxin family with disulfide reductase activity: Implication in the redox regulation of TNF-alpha signaling.
TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.
Neuroblastoma
Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin-related protein 14-mediated autophagy.
Ovarian Neoplasms
TRP14 promotes resistance to cisplatin by inducing autophagy in ovarian cancer.
TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.