1.8.1.16: glutathione amide reductase
This is an abbreviated version!
For detailed information about glutathione amide reductase, go to the full flat file.
Reaction
Synonyms
GAR, garB
ECTree
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Systematic Name
Systematic Name on EC 1.8.1.16 - glutathione amide reductase
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glutathione amide:NAD+ oxidoreductase
A dimeric flavoprotein (FAD). The enzyme restores glutathione amide disulfide, which is produced during the reduction of peroxide by EC 1.11.1.17 (glutathione amide-dependent peroxidase), back to glutathione amide (it catalyses the reaction in the opposite direction to that shown). The enzyme belongs to the family of flavoprotein disulfide oxidoreductases, but unlike other members of the family, which are specific for NADPH, it prefers NADH [1].