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1.8.1.15: mycothione reductase

This is an abbreviated version!
For detailed information about mycothione reductase, go to the full flat file.

Word Map on EC 1.8.1.15

Reaction

2 mycothiol +

NAD(P)+
=
mycothione
+
NAD(P)H
+
H+

Synonyms

MSH disulfide reductase, MtMtr, MTR, mycothiol disulfide reductase, mycothiol disulphide reductase, mycothiol-disulfide reductase, mycothione disulphide reductase, mycothione reductase, NADPH-dependent mycothiol reductase, NADPH-dependent mycothione reductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.15 mycothione reductase

KM Value

KM Value on EC 1.8.1.15 - mycothione reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4
2,6-dimethylbenzoquinone
-
0.463
2-(-N-acetyl-L-cysteinyl) amino-2-deoxy-alpha-D-glucopyranoside disulfide
-
30°C, pH 7.5
0.24
2-methyl-1,4-naphthoquinone
-
0.34
5,8-Dihydroxy-1,4-naphthoquinone
-
0.268
5-(benzyl 2-(N-acetyl-L-cysteinyl) amino-2-deoxy-alpha-D-glucopyranoside)-dithio-2-nitrobenzoate
-
-
0.54
5-hydroxy-1,4-naphthoquinone
-
2.365
7-methyljuglone
-
pH 7.6, 30°C
0.142
8-chloro-5-methoxy-7-methyl-1,4-naphthoquinone
-
pH 7.6, 30°C
0.055
alpha-NADPH
des-myo-inositol mycothione as second substrate
0.438
benzyl 2-(-N-acetyl-L-cysteinyl) amino-2-deoxy-alpha-D-glucopyranoside disulfide
-
30°C, pH 7.5
0.438
benzyl 2-(N-acetyl-L-cysteinyl) amino-2-deoxy-alpha-D-glucopyranoside disulfide
-
-
0.008
beta-NADPH
des-myo-inositol mycothione as second substrate
0.4 - 0.51
des-myo-inositol mycothione
0.118
diospyrin
-
pH 7.6, 30°C
1.088
juglone
-
pH 7.6, 30°C
0.732
menadione
-
pH 7.6, 30°C
0.61
methyl 2-(-N-acetyl-L-cysteinyl) amino-2-deoxy-alpha-D-glucopyranoside disulfide
-
30°C, pH 7.5
0.073 - 0.113
mycothione
0.043
NADH
des-myo-inositol mycothione as second substrate
0.308
neodiospyrin
-
pH 7.6, 30°C
0.2
reduced beta-nicotinamide hypoxanthine dinucleotide
des-myo-inositol mycothione as second substrate
0.023
reduced beta-nicotinamide hypoxanthine dinucleotide phosphate
des-myo-inositol mycothione as second substrate
35.23 - 43.9
SeO32-
0.413 - 0.779
TeO32-
-
0.09
thio-NADH
des-myo-inositol mycothione as second substrate
0.001
thio-NADPH
des-myo-inositol mycothione as second substrate
additional information
additional information
-