1.7.3.3: factor-independent urate hydroxylase

This is an abbreviated version!
For detailed information about factor-independent urate hydroxylase, go to the full flat file.

Word Map on EC 1.7.3.3

Reaction

Urate
+
O2
+
H2O
=
5-hydroxyisourate
+
H2O2

Synonyms

AaUO, AgUOX, ELITEK, Fasturtec, N-35, Nodule specific uricase, Nodulin 35, Nodulin 35 homolog, Non-symbiotic uricase, oxidase, urate, Rasburicase, Uaz, Uox, Urate oxidase, urate oxidoreductase, UriA, uric acid oxidase, uricase, uricase II, Uricoenzyme, Uricozyme

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.3 With oxygen as acceptor
                1.7.3.3 factor-independent urate hydroxylase

Expression

Expression on EC 1.7.3.3 - factor-independent urate hydroxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression is induced in presence of urate; expression is induced in presence of urate, with substrate inhibition of production above 8.9 mM
highest expression yields are obtained in medium containing 0.8% maltose and 1.2% soybean powder as carbon and nitrogen sources, respectively
maximum expression upon growth on lactose as carbon source and urea as nitrogen source
optimum uricase production is in basal medium containing sucrose as a sole carbon source, uric acid as a nitrogen source at pH 6. Presence of cysteine HCl, cystine and glutamic acid enhances uricase production