1.7.1.B3: aromatic nitroreductase [NADPH]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NADPH], go to the full flat file.

Word Map on EC 1.7.1.B3

Reaction

an aromatic amine
+ 3 NADP+ + 2 H2O =
an aromatic nitrate
+ 3 NADPH + 3 H+

Synonyms

ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, oxygen-insensitive nitroreductase (NADPH)

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B3 aromatic nitroreductase [NADPH]

Substrates Products

Substrates Products on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,4,6-trinitrotoluene + NADPH + H+
4-hydroxylamino-2,6-dinitrotoluene + NADP+ + H2O
show the reaction diagram
2,4,6-trinitrotoluene + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
2,4-dinitrotoluene + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
-
-
-
?
2-amino-4,6-dinitrotoluene + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
4-amino-2,6-dinitrotoluene + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
5-(aziridin-1-yl)-2,4-dinitrobenzamide + NADPH + H+
? + NADP+
show the reaction diagram
m-dinitrobenzene + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
methyl 4-nitrobenzoate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
nifuroxime + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
nitro-CBI-5-[(dimethylamino)ethoxy]indole + NAD(P)H + H+
? + NAD(P)+
show the reaction diagram
-
a nitro-CBI prodrug, low activity
-
-
?
nitrobenzene + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
nitrofurantoin + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
nitrofurazone + NADPH + H+
5-(hydroxyamino)furan-2-carbaldehyde semicarbazone + NADP+ + H2O
show the reaction diagram
o-dinitrobenzene + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
p-dinitrobenzene + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
p-nitroacetophenone + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
p-nitrobenzaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
p-nitrobenzoic acid + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
tetryl + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
additional information
?
-