1.7.1.B3: aromatic nitroreductase [NADPH]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NADPH], go to the full flat file.

Word Map on EC 1.7.1.B3

Reaction

an aromatic amine
+ 3 NADP+ + 2 H2O =
an aromatic nitrate
+ 3 NADPH + 3 H+

Synonyms

ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, oxygen-insensitive nitroreductase (NADPH)

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B3 aromatic nitroreductase [NADPH]

Specific Activity

Specific Activity on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.1
-
purified recombinant mutant F46A, pH 7.0, 22C, substrate nitrofurazone
0.29
-
purified recombinant mutant F46N, pH 7.0, 22C, substrate nitrofurazone
3.74
-
purified recombinant mutant F46Y, pH 7.0, 22C, substrate nitrofurazone
7.75
-
purified recombinant wild-type enzyme, pH 7.0, 22C, substrate nitrofurazone
52.5
-
purified recombinant untagged enzyme, pH 7.0, 23C