1.7.1.B3: aromatic nitroreductase [NADPH]
This is an abbreviated version!
For detailed information about aromatic nitroreductase [NADPH], go to the full flat file.
Word Map on EC 1.7.1.B3
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1.7.1.B3
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hypoplasia
-
dermal
-
x-linked
-
goltz
-
ectodermal
-
malformation
-
ocular
-
porcupine
-
mesoderm
-
blaschko
-
skew
-
x-chromosome
-
postzygotic
-
teeth
-
goltz-gorlin
-
multisystemic
-
herniation
-
diaphragmatic
-
x-inactivation
-
angioma
-
papillomas
-
hernia
-
wingless
-
cutis
-
nail
-
o-acyltransferase
-
aplasia
-
patchy
-
environmental protection
-
medicine
- 1.7.1.B3
-
hypoplasia
-
dermal
-
x-linked
-
goltz
-
ectodermal
-
malformation
-
ocular
-
porcupine
-
mesoderm
-
blaschko
-
skew
-
x-chromosome
-
postzygotic
-
teeth
-
goltz-gorlin
-
multisystemic
-
herniation
-
diaphragmatic
-
x-inactivation
-
angioma
-
papillomas
-
hernia
-
wingless
-
cutis
-
nail
-
o-acyltransferase
-
aplasia
-
patchy
- environmental protection
- medicine
Reaction
+ 3 NADP+ + 2 H2O = + 3 NADPH + 3 H+
Synonyms
ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, NR-A, ORF 17150, oxygen-insensitive NAD(P)H:nitroreductases, oxygen-insensitive nitroreductase (NADPH)
ECTree
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Reference
Reference on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]
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Valiauga, B.; Williams, E.M.; Ackerley, D.F.; Cenas, N.
Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA) Characterization of kinetics and substrate specificity
Arch. Biochem. Biophys.
614
14-22
2017
Escherichia coli
Zenno, S.; Kobori, T.; Tanokura, M.; Saigo, K.
Purification and characetrizatio of NfrA1, a Bacillus subtilis nitro/flavin reductase capable of interacting with the bacterial luciferase
Biosci. Biotechnol. Biochem.
62
1978-1987
1998
Bacillus subtilis, Bacillus subtilis ISW 1214
Yang, J.; Zhan, J.; Bai, J.; Liu, P.; Xue, Y.; Yang, Q.
Residue Phe42 is critical for the catalytic activity of Escherichia coli major nitroreductase NfsA
Biotechnol. Lett.
35
1693-1700
2013
Escherichia coli (P17117)
Green, L.K.; Syddall, S.P.; Carlin, K.M.; Bell, G.D.; Guise, C.P.; Mowday, A.M.; Hay, M.P.; Smaill, J.B.; Patterson, A.V.; Ackerley, D.F.
Pseudomonas aeruginosa NfsB and nitro-CBI-DEI - a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy
Mol. Cancer
12
58
2013
Escherichia coli (P17117)
Bai, J.; Yang, J.; Liu, P.; Yang, Q.
Transformation pathway of 2,4,6-trinitrotoluene by Escherichia coli nitroreductases and improvement of activity using structure-based mutagenesis
Process Biochem.
50
705-711
2015
Escherichia coli (P17117)
Valiauga, B.; Miseviciene, L.; Rich, M.H.; Ackerley, D.F.; Sarlauskas, J.; Cenas, N.
Mechanism of two-/four-electron reduction of nitroaromatics by oxygen-insensitive nitroreductases the role of a non-enzymatic reduction step
Molecules
23
1672
2018
Escherichia coli
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