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1.7.1.B3: aromatic nitroreductase [NADPH]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NADPH], go to the full flat file.

Word Map on EC 1.7.1.B3

Reaction

an aromatic amine
+ 3 NADP+ + 2 H2O =
an aromatic nitrate
 + 3 NADPH + 3 H+

Synonyms

ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, NR-A, ORF 17150, oxygen-insensitive NAD(P)H:nitroreductases, oxygen-insensitive nitroreductase (NADPH)

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B3 aromatic nitroreductase [NADPH]

KM Value

KM Value on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.013 - 0.033
2,4,6-trinitrotoluene
0.176 - 0.366
2,4-dinitrotoluene
0.3257
2-amino-4,6-dinitrotoluene
pH 7.0, 37°C, recombinant His6-tagged enzyme
0.6427
4-amino-2,6-dinitrotoluene
pH 7.0, 37°C, recombinant His6-tagged enzyme
0.23 - 0.487
5-(aziridin-1-yl)-2,4-dinitrobenzamide
0.046
m-dinitrobenzene
-
pH 7.0, 25°C
0.00085 - 0.085
NADPH
0.031
nifuroxime
-
pH 7.0, 25°C
1.5
nitrobenzene
-
pH 7.0, 25°C
0.019
Nitrofurantoin
-
pH 7.0, 25°C
0.012 - 0.064
nitrofurazone
0.018
o-dinitrobenzene
-
pH 7.0, 25°C
0.037
p-dinitrobenzene
-
pH 7.0, 25°C
0.39
p-nitroacetophenone
-
pH 7.0, 25°C
0.17
p-nitrobenzaldehyde
-
pH 7.0, 25°C
2.5
p-nitrobenzoic acid
-
pH 7.0, 25°C
0.011
tetryl
-
pH 7.0, 25°C
additional information
additional information
-