1.7.1.B3: aromatic nitroreductase [NADPH]

This is an abbreviated version, for detailed information about aromatic nitroreductase [NADPH], go to the full flat file.

Reaction

an aromatic amine
+ 3 NADP+ + 2 H2O =
an aromatic nitrate
+ 3 NADPH + 3 H+

Synonyms

ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, oxygen-insensitive nitroreductase (NADPH)

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B3 aromatic nitroreductase [NADPH]

KCat KM Value

KCat KM Value on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
50 - 2697
2,4,6-trinitrotoluene
2 - 142
2,4-dinitrotoluene
38
2-amino-4,6-dinitrotoluene
-
pH 7.0, 37°C, recombinant His6-tagged enzyme
1.6
4-amino-2,6-dinitrotoluene
-
pH 7.0, 37°C, recombinant His6-tagged enzyme
-
2 - 112
5-(aziridin-1-yl)-2,4-dinitrobenzamide
1195.7
m-dinitrobenzene
-
pH 7.0, 25°C
-
5 - 191.7
NADPH
5806.5
nifuroxime
-
pH 7.0, 25°C
9.3
nitrobenzene
-
pH 7.0, 25°C
7157.9
Nitrofurantoin
-
pH 7.0, 25°C
10 - 1610
nitrofurazone
3333.3
o-dinitrobenzene
-
pH 7.0, 25°C
-
729.7
p-dinitrobenzene
-
pH 7.0, 25°C
-
151.3
p-nitroacetophenone
-
pH 7.0, 25°C
176.5
p-nitrobenzaldehyde
-
pH 7.0, 25°C
25.6
p-nitrobenzoic acid
-
pH 7.0, 25°C
7727.27
tetryl
-
pH 7.0, 25°C
-