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1.7.1.B2: aromatic nitroreductase [NAD(P)H]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NAD(P)H], go to the full flat file.

Reaction

an aromatic amine
+ 3 NAD(P)+ + 2 H2O =
an aromatic nitrate
+ 3 NAD(P)H + 3 H+

Synonyms

NfnB, NfsB, NfsB_Ec, NfsB_Pa, NprA, oxygen-insensitive nitroreductase (NAD(P)H), YfkO

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B2 aromatic nitroreductase [NAD(P)H]

General Information

General Information on EC 1.7.1.B2 - aromatic nitroreductase [NAD(P)H]

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
nitroreductases are a family of flavoproteins that catalyze the NAD(P)H-dependent reduction of nitro groups to hydroxyamino and/or amino groups on vari-ous nitro-substituted compounds
physiological function
additional information
the enzyme crystal structure of NfsB, PDB ID 1DS7, is used for molecular ligand docking studies