Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.7.1.3: nitrate reductase (NADPH)

This is an abbreviated version!
For detailed information about nitrate reductase (NADPH), go to the full flat file.

Word Map on EC 1.7.1.3

Reaction

nitrite
+
NADP+
+
H2O
=
nitrate
+
NADPH
+
H+

Synonyms

assimilatory NADPH-nitrate reductase, assimilatory NADPH:nitrate reductase, Assimilatory nitrate reductase, assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase, EC 1.6.6.3, EC 1.7.99.4, MSMEG_2837, NADPH-dependent nitrate reductase, NADPH-nitrate reductase, NADPH2:nitrate oxidoreductase, NADPH:nitrate reductase, NADPH:NR, NaR1, narB, nit-3, nitrate reductase, nitrate reductase (NADPH), nitrate reductase (reduced nicotinamide adenine dinucleotide phosphate), nitrate reductase [NADPH], NR, triphosphopyridine nucleotide-nitrate reductase

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.3 nitrate reductase (NADPH)

Inhibitors

Inhibitors on EC 1.7.1.3 - nitrate reductase (NADPH)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
8-hydroxyquinoline
azide
cyanide
iodoacetamide
-
pH 7.5, 40% inhibition at 1 mM
NADP+
-
inhibits NADPH oxidation, non-competitive with respect to nitrate
NADPH
NH4+
-
inhibits the enzyme under aerobic conditions
nitrite
-
competitive with respect to nitrate and non-competitive to NADPH
o-phenanthroline
-
-
p-chloromercuribenzoate
p-hydroxymercuribenzoate
phenanthroline hydrate
-
pH 7.5, 1:10, 20% inhibition at 0.1 mM
Phenylglyoxal
-
in 0.1 M phosphate, pH 7.3, 4 mM, inactivation after 15 min to 40% and to 20% after 60 min
potassium chlorate
-
pH 7.5, slight, 20% inhibition at 5 mM
potassium ethyl xanthate
-
-
Sodium nitrite
-
pH 7.5, slight, 50% inhibition at 5 mM
Thiourea
-
-
additional information
-