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1.7.1.13: preQ1 synthase

This is an abbreviated version!
For detailed information about preQ1 synthase, go to the full flat file.

Word Map on EC 1.7.1.13

Reaction

7-aminomethyl-7-carbaguanine
+ 2 NADP+ =
7-cyano-7-carbaguanine
+ 2 NADPH + 2 H+

Synonyms

7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase, 7-cyano-7-deazaguanine reductase, NADPH-dependent 7-cyano-7-deazaguanine reductase, nitrile reductase, NRed, preQ0 reductase, preQ0oxidoreductase, QueF, queuine synthase, YkvM

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.13 preQ1 synthase

KM Value

KM Value on EC 1.7.1.13 - preQ1 synthase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0061
2-amino-5-cyanopyrrolo[2,3-d]pyrimidin-4-one
wild-type, pH 7.5, 25°C
0.176
5-cyanopyrrolo[2,3-d]pyrimidin-4-one
wild-type, pH 7.5, 25°C
0.05
7-cyano-7-carba-2-deaminoguanine
-
pH 7.5, 25°C
0.00025 - 0.001
7-cyano-7-carbaguanine
0.0015
7-cyano-7-deazaguanine
or below, pH 7.0, 37°C
0.0002 - 0.229
NADPH