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1.6.5.5: NADPH:quinone reductase

This is an abbreviated version!
For detailed information about NADPH:quinone reductase, go to the full flat file.

Word Map on EC 1.6.5.5

Reaction

NADPH
+
H+
 + 2 quinone =
NADP+
 + 2 semiquinone

Synonyms

ArsH, Dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate) (quinone), DT-diaphorase, EC 1.6.99.2, Flavoprotein NAD(P)H:quinone reductase, Menadione oxidoreductase, Menadione reductase, NAD(P)H dehydrogenase, NAD(P)H dehydrogenase (quinone), NAD(P)H menadione reductase, NAD(P)H quinone reductase, NAD(P)H-quinone dehydrogenase, NAD(P)H-quinone oxidoreductase, NAD(P)H-quinone reductase, NAD(P)H:(quinone-acceptor) oxidoreductase, NAD(P)H:menadione oxidoreductase, NAD(P)H:paraquat diaphorase, NAD(P)H:quinone reductase, NADH-menadione reductase, NADH-menaquinone reductase, NADH:quinone reductase, NADPH DT-diaphorase, NADPH quinone acceptor oxidoreductase, NADPH-dependent quinone reductase, NADPH:azodicarbonyl/quinone reductase, NADPH:quinone oxidoreductase, NADPH:quinone reductase, Naphthoquinone reductase, NfsA, nitroreductase A, old yellow enzyme, ORF 17150, p-Benzoquinone reductase, P1-ZCr, P1-zeta-crystallin, P36, PA0660, Phylloquinone reductase, PtoQOR, QAO, Qor, QorA, Quinone reductase, Reduced NAD(P)H dehydrogenase, TcOYE, TmQR1, VAT-1, vesicle amine transport protein-1, Viologen accepting pyridine nucleotide oxidoreductase, Vitamin K reductase, ZCr, zeta-Crystallin, zeta-crystallin homolog protein, zeta-crystallin/NADPH:quinone oxidoreductase, zeta-Crystallin/quinone reductase, Zta1, Zta1p

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.5 NADPH:quinone reductase

KCat KM Value

KCat KM Value on EC 1.6.5.5 - NADPH:quinone reductase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
250 - 5636.4
1,4-benzoquinone
100
1,4-dihydroxy-9,10-anthraquinone
-
pH 7.0, 25°C
1250 - 1393.9
1,4-Naphthoquinone
106.7
1,8-dihydroxy-9,10-anthraquinone
-
pH 7.0, 25°C
30
2,3,4,6-tetramethyl-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
-
2772.7
2,3-dichloro-1,4-naphthoquinone
-
pH 7.0, 25°C
130
2,3-dimethoxy-5-methyl-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
16
2,6-dimethoxy-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
3187.5
2,6-dimethyl-1,4-benzoquinone
-
pH 7.0, 25°C
0.0016 - 0.06
2-hexenal
10909.1
2-Hydroxy-1,4-naphthoquinone
-
pH 7.0, 25°C
8750
2-hydroxy-3-methyl-1,4-naphthoquinone
-
pH 7.0, 25°C
6750
2-methyl-1,4-benzoquinone
-
pH 7.0, 25°C
276.9 - 300
2-methyl-1,4-naphthoquinone
0.23
2-nonenal
pH 7, 25°C, wild-type
0.023
2-pentenal
pH 7, 25°C, wild-type
0.13 - 4.8
3-buten-2-one
0.016 - 0.23
3-nonen-2-one
0.025 - 0.36
3-penten-2-one
0.023 - 10.21
4-hydroxy-2-hexenal
2.1
4-hydroxy-2-nonenal
pH 7, 25°C, wild-type
13333
5,8-Dihydroxy-1,4-naphthoquinone
-
pH 7.0, 25°C
1100 - 13750
5-hydroxy-1,4-naphthoquinone
18.9
9,10-anthraquinone-2-sulfonic acid
-
pH 7.0, 25°C
37.8
9,10-phenanthrenequinone
pH 7.8, 25°C
50
NADH
1000 - 1300
NADPH
0.058 - 1.5
propenal
262.5
riboflavin
-
pH 7.0, 25°C
2.7
tetramethyl-1,4-benzoquinone
-
pH 7.0, 25°C