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1.6.5.2: NAD(P)H dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about NAD(P)H dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.6.5.2

Reaction

NAD(P)H
+
H+
 +
a quinone
=
NAD(P)+
 +
a hydroquinone

Synonyms

1,4-benzoquinone reductase, azoreductase, chromate reductase, ChrR, dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone), diaphorase, DPND, DPNH-diaphorase, DT-diaphorase, DTD, DVU_2399, DVU_2400, DVU_2401, EC 1.6.99.2, FerB, ferric reductase B, flavoprotein NAD(P)H-quinone reductase, FlxABCD, FMN-dependent NAD(P)H:quinone oxidoreductase, Internal NADH dehydrogenase, MdaB, Menadione oxidoreductase, Menadione reductase, NAD(P)H dehydrogenase, NAD(P)H dehydrogenase complex, NAD(P)H menadione reductase, NAD(P)H quinone oxidoreductase, NAD(P)H quinone oxidoreductase-1, NAD(P)H quinone oxidoreductase1, NAD(P)H quinone reductase, NAD(P)H quinone-oxidoreductase 1, NAD(P)H-QR, NAD(P)H-quinone dehydrogenase, NAD(P)H-quinone oxidoreductase, NAD(P)H: (quinone acceptor) oxidoreductase, NAD(P)H: (quinone-acceptor)oxidoreductase, NAD(P)H: menadione oxidoreductase, NAD(P)H: Quinone oxidoreductase, NAD(P)H: quinone oxidoreductase 1, NAD(P)H: quinone oxidoreductase-1, NAD(P)H: quinone reductase, NAD(P)H:acceptor oxidoreductase, NAD(P)H:quinone acceptor oxidoreductase, NAD(P)H:quinone oxidoreducatase 1, NAD(P)H:quinone oxidoreductase, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxidoreductase I, NAD(P)H:quinone oxidoreductase-1, NAD(P)H:quinone reductase, NAD(P)H:quinoneoxidoreductase 1, NADH-menadione reductase, NADH:quinone oxidoreductase 1, NADPH quinone reductase, NADPH: quinone oxidoreductase-1, NADPH:quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NAD[P]H:quinone acceptor oxidoreductase 1, Naphthoquinone reductase, Ndh complex, NDH2, nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase 1, NQO1, NQR, NRH:quinone reductase 1, p-Benzoquinone reductase, Pden_4071, PfNdh2, Phylloquinone reductase, QOR2, QR1, QR2, Quinone reductase, quinone reductase 1, quinone reductase type 1, Reduced NAD(P)H dehydrogenase, reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase, TcpB, TmQR2, type II NADH: quinone oxidoreductase, Viologen accepting pyridine nucleotide oxidoreductase, Vitamin K reductase, vitamin-K reductase, WrbA

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.2 NAD(P)H dehydrogenase (quinone)

KM Value

KM Value on EC 1.6.5.2 - NAD(P)H dehydrogenase (quinone)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0058 - 0.037
1,4-benzoquinone
0.0208
2,5-di-tert-butyl-1,4-benzoquinone
pH 6.0, temperature not specified in the publication
0.0105
2,6-dichlorophenolindophenol
pH 6.0, temperature not specified in the publication
0.0074
2,6-dimethoxy-1,4-benzoquinone
pH 6.0, temperature not specified in the publication
0.0024
2-methoxy-1,4-benzoquinone
pH 6.0, temperature not specified in the publication
0.115
2-methoxy-5-(methoxymethyl)-2,5-cyclohexadiene
-
-
0.115
2-methoxy-5-(methoxymethyl)-2,5-cyclohexadiene-1,4-dione
-
-
0.025 - 0.04
5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-dione
0.26 - 1.37
5-(aziridin-1-yl)-2,4-dinitrobenzamide
0.84 - 1.37
5-(aziridin-1-yl)-4-hydroxylamino-2-benzamide
0.11 - 36.3
benzoquinone
0.26
chromate(IV)
-
pH 5.0, 70°C
0.12
coenzyme Q1
-
pH 8.5, 60°C
0.21 - 0.435
duroquinone
0.0000017 - 0.0000027
FAD
0.0025 - 0.0096
FMN
0.000188 - 0.23
menadione
0.0047 - 0.028
Methyl red
0.024
methylene blue
-
cofactor NADPH
0.005 - 125
NADH
0.03 - 0.403
NADPH
0.000437 - 0.00059
naphthoquinone
0.007 - 0.018
oxidized 2,6-dichloroindophenol
0.0233
oxidized 2,6-dichlorophenolindophenol
-
-
0.012
oxidized 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
-
recombinant NAD(P)H:quinone acceptor oxidoreductase 2
-
1.4 - 1.7
potassium ferricyanide
0.028 - 0.07
reduced dihydronicotinamide riboside
-
0.0143
reduced nicotinamide 2-azidoadenine dinucleotide
-
-
0.0185
reduced nicotinamide 8-azidoadenine dinucleotide
-
-
0.0065
ubiquinone-0
-
in 10 mM bis-Tris-propane buffer (pH 7.2), at 25°C
0.0641 - 0.33
vitamin K1
additional information
additional information
-