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1.6.5.10: NADPH dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about NADPH dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.6.5.10

Reaction

NADPH
+
H+
 +
a quinone
=
NADP+
 +
a quinol

Synonyms

AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), EC 1.6.99.6, MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, NADPH quinone reductase, NADPH-dependent quinone reductase, NADPH-quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NQO1, PA1225, PpAzoR, XAC2229, Zta1p

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.10 NADPH dehydrogenase (quinone)

KM Value

KM Value on EC 1.6.5.10 - NADPH dehydrogenase (quinone)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.003 - 0.009
1,2-naphthoquinone
0.0019 - 1.8
1,4-benzoquinone
0.0065
1,4-Naphthoquinone
-
pH 7.4, 25°C
298.2
2,3-dichloro-5,6-dicyano-1,4-benzoquinone
25°C, pH 6.5
0.0044
2,3-dimethoxy-5-methyl-1,4-benzoquinone
-
pH 7.4, 25°C
0.0013
2,5-dimethyl-4-benzoquinone
-
pH 8.0, 25°C, recombinant His-tagged enzyme
0.0237
2-Hydroxy-1,4-naphthoquinone
-
pH 8.0, 25°C, recombinant His-tagged enzyme
0.003
2-methyl-1,4-naphthoquinone
-
pH 7.4, 25°C
0.0045
5-hydroxy-1,4-naphthoquinone
-
pH 7.4, 25°C
0.0043
5-Hydroxy-2-methyl-1,4-naphthoquinone
-
pH 7.4, 25°C
0.0016 - 0.056
9,10-phenanthrenequinone
0.0345
anthraquinone-2-sulfonate
-
pH 8.0, 25°C, recombinant His-tagged enzyme
0.0119
coenzyme Q10
-
pH 8.0, 25°C, recombinant His-tagged enzyme
0.0012
dibromothymoquinone
-
pH 8.0, 25°C, recombinant His-tagged enzyme
0.0028 - 0.019
duroquinone
647.5
hydroquinone
25°C, pH 6.5
0.0057 - 0.036
menadione
0.006 - 0.17
NADPH
728.6
phenyl-1,4-benzoquinone
25°C, pH 6.5
additional information
additional information
-