1.6.3.4: NADH oxidase (H2O-forming)
This is an abbreviated version!
For detailed information about NADH oxidase (H2O-forming), go to the full flat file.
Reaction
2 NADH
+
2 H+
+
Synonyms
H2O-forming NADH oxidase, LrNox, NADH oxidase, nicotinamide adenine dinucleotide oxidase, NOX, Nox-2, NoxA, NoxE, SpNox, water-forming NADH oxidase, YODC
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1.6.3.4 NADH oxidase (H2O-forming)Advanced search results
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Substrates Products on EC 1.6.3.4 - NADH oxidase (H2O-forming)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme is involved detoxification of oxygen to water
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme can catalyze electron transfers from NADH to ferricyanide, 2,6-dichloroindophenol, and menadione, although the activities with these acceptors are extremely low relative to O2. Thus, O2 must be a natural electron acceptor for this enzyme
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme is involved detoxification of oxygen to water
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme can catalyze electron transfers from NADH to ferricyanide, 2,6-dichloroindophenol, and menadione, although the activities with these acceptors are extremely low relative to O2. Thus, O2 must be a natural electron acceptor for this enzyme
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
-
the enzyme is highly specific for NADH, no activity with NADPH. O2 is the preferred electron acceptor, in addition FAD and, very slowly, one-electron acceptors are reduced. NO formation of H2O2
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
Streptococcus mutans NCBI 11723 contains two distinct NADH oxidase, a H2O2-forming and a H2O-forming enzyme
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme is highly specific for NADH, no activity with NADPH
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
Streptococcus mutans NCBI 11723 contains two distinct NADH oxidase, a H2O2-forming and a H2O-forming enzyme
-
-
?
2 NADH + H+ + O2
NAD+ + 2 H2O
the enzyme is highly specific for NADH, no activity with NADPH
-
-
?
BNAH + H+ + O2
BNA+ + H2O
i.e. N-benzyl-1,4-dihydronicotinamide
-
-
?
BNAH + H+ + O2
BNA+ + H2O
i.e. N-benzyl-1,4-dihydronicotinamide
-
-
?
MNAH + H+ + O2
MNA+ + H2O
i.e. N-methyl-1,4-dihydronicotinamide
-
-
?
MNAH + H+ + O2
MNA+ + H2O
i.e. N-methyl-1,4-dihydronicotinamide
-
-
?
NADH + H+ + oxidized methylene blue
NAD+ + reduced methylene blue
-
-
-
?
NADH + H+ + oxidized methylene blue
NAD+ + reduced methylene blue
Lactococcus cremoris MG1363
-
-
-
?
additional information
?
-
NADPH can be recognized as a substrate by the enzyme, though the specific activity is only about 2% compared to NADH
-
-
?
additional information
?
-
-
NADPH can be recognized as a substrate by the enzyme, though the specific activity is only about 2% compared to NADH
-
-
?
additional information
?
-
NADPH can be recognized as a substrate by the enzyme, though the specific activity is only about 2% compared to NADH
-
-
?
