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1.5.99.4: nicotine dehydrogenase

This is an abbreviated version!
For detailed information about nicotine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.99.4

Reaction

(S)-nicotine
+
acceptor
+
H2O
=
(S)-6-hydroxynicotine
+
reduced acceptor

Synonyms

6-hydroxy-D-nicotine oxidase, 6-hydroxy-L-nicotine oxidase, D-nicotine oxidase, NctA, NDH, NdhAB, nicotine dehydrogenase, nicotine oxidase, nicotinic acid hydroxylase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.99 With unknown physiological acceptors
                1.5.99.4 nicotine dehydrogenase

KM Value

KM Value on EC 1.5.99.4 - nicotine dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00087 - 0.035
(S)-nicotine
0.00124 - 1.24
2,6-dichlorophenolindophenol
0.008
brilliant cresyl blue
-
-
0.49
menadione
-
-
0.027
methylene blue
-
-
0.037
Nicotine
-
-
0.00361
pseudoazurin
-
pH 7, 30°C
-
additional information
additional information
-