1.5.99.4: nicotine dehydrogenase
This is an abbreviated version!
For detailed information about nicotine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.99.4
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1.5.99.4
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arthrobacter
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molybdopterins
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barkeri
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nicotinovorans
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molybdenum
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xanthine
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6-hydroxynicotine
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selenium-containing
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selenocysteine
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molybdenum-containing
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selenoproteins
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selenide
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nicotine-degrading
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6-hydroxy-l-nicotine
- 1.5.99.4
- arthrobacter
- molybdopterins
- barkeri
- nicotinovorans
- molybdenum
- xanthine
- 6-hydroxynicotine
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selenium-containing
- selenocysteine
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molybdenum-containing
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selenoproteins
- selenide
-
nicotine-degrading
- 6-hydroxy-l-nicotine
Reaction
Synonyms
6-hydroxy-D-nicotine oxidase, 6-hydroxy-L-nicotine oxidase, D-nicotine oxidase, NctA, NDH, NdhAB, nicotine dehydrogenase, nicotine oxidase, nicotinic acid hydroxylase
ECTree
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General Information
General Information on EC 1.5.99.4 - nicotine dehydrogenase
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malfunction
metabolism
physiological function
additional information
a nox disruption mutant of strain HZN6 loses the ability to degrade nicotine, but not pseudooxynicotine
malfunction
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a nox disruption mutant of strain HZN6 loses the ability to degrade nicotine, but not pseudooxynicotine
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the enzyme is responsible for the first step of nicotine degradation
metabolism
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the enzyme is responsible for the first step of nicotine degradation
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the enzyme nonenantioselectively degrades nicotine to pseudooxynicotine
physiological function
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disruption of the gene encoding pseudoazurin disables nicotine degradation
physiological function
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the enzyme nonenantioselectively degrades nicotine to pseudooxynicotine
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physiological function
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disruption of the gene encoding pseudoazurin disables nicotine degradation
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the conserved FAD-binding GXGXXG motif and His456 are essential for nicotine degradation activity
additional information
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the conserved FAD-binding GXGXXG motif and His456 are essential for nicotine degradation activity
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