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1.5.5.3: hydroxyproline dehydrogenase

This is an abbreviated version!
For detailed information about hydroxyproline dehydrogenase, go to the full flat file.

Word Map on EC 1.5.5.3

Reaction

trans-4-hydroxy-L-proline
+
a quinone
=
(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate
+
a quinol

Synonyms

HPOX, hydroxyproline oxidase, HYPDH, OH-POX, ProDH2, proline dehydrogenase 2

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.5 With a quinone or similar compound as acceptor
                1.5.5.3 hydroxyproline dehydrogenase

Disease

Disease on EC 1.5.5.3 - hydroxyproline dehydrogenase

Please use the Disease Search for a specific query.
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Hyperoxaluria, Primary
Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria.
Re: The Effects of the Inactivation of Hydroxyproline Dehydrogenase on Urinary Oxalate and Glycolate Excretion in Mouse Models of Primary Hyperoxaluria.
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.