1.5.5.2: proline dehydrogenase

This is an abbreviated version!
For detailed information about proline dehydrogenase, go to the full flat file.

Word Map on EC 1.5.5.2

Reaction

L-proline
+
a quinone
=
(S)-1-pyrroline-5-carboxylate
+
a quinol

Synonyms

bifunctional dye-linked L-proline/NADH dehydrogenase complex, dye-linked L-proline dehydrogenase, FAD-dependent L-proline oxidoreductase, JcProDH, L-proline dehydrogenase, L-proline:FAD oxidoreductase, PdhB, PDHbeta, PF1246, PF1798, PH1364, PH1751, PRODH, proDH-B1, proDH-B2, PRODH/POX, ProDH1, proline dehydrogenase, proline dehydrogenase 1, proline dehydrogenase/oxidase, proline oxidase, proline/P5C dehydrogenase, prub, PutA, PutA flavoprotein, PutA proline dehydrogenase, Tc00.1047053506411.30, TcPRODH, TK0117, TK0122, TPpdhbeta, TtProDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.5 With a quinone or similar compound as acceptor
                1.5.5.2 proline dehydrogenase

Expression

Expression on EC 1.5.5.2 - proline dehydrogenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
isoform ProDH1 expression is dependent on salicylic acid (stimulation at 0.05-2.5 mM) and an increase in enzyme activity is detected in cells destined to die
-
L-proline treatment induces ProDH in planta. Induction of D-lactate dehydrogenase activity allows rapid upregulation of ProDH activity during the short-term stress response in plants. Transcriptional induction of the enzyme causes changes in expression levels of other mitochondrial enzymes
-
ProDH activity is high for genotypes in which ProDH, most likely ProDH1, is strongly induced by L-proline
proline and NaCl induce gene expression
-
salicylic acid has no effect on the isoform ProDH2 mRNA level, even at 2.5 mM
-
sucrose represses ProDH2 expression
-
TcPRODH mRNA and protein expression are strongly upregulated in the intracellular epimastigote, a stage which requires an external supply of proline
the expression of JcProDH increases in leaves experiencing environmental stress such as cold (5C), heat (42C), salt (300 mM), and drought (30% PEG 6000)