1.5.4.1: pyrimidodiazepine synthase

This is an abbreviated version!
For detailed information about pyrimidodiazepine synthase, go to the full flat file.

Reaction

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one

+ 2 glutathione

Synonyms

More, PDA synthase

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.4 With a disulfide as acceptor

1.5.4.1 pyrimidodiazepine synthase

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Results	in table
1	Activating Compound
2	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
2	KM Value [mM]
4	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
3	Organism
4	Pathway
1	Purification (Commentary)
2	Reaction
3	Reaction Type
3	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
2	Storage Stability
8	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Reference

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Reference on EC 1.5.4.1 - pyrimidodiazepine synthase

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437751

Wiederrecht, G.J.; Brown, G.M.

Purification and properties of the enzymes from Drosophila melanogaster that catalyze the conversion of dihydroneopterin triphosphate to the pyrimidodiazepine precursor of the drosopterins

J. Biol. Chem.

259

14121-14127

1984

Drosophila melanogaster

6438092

656799

Giordano, E.; Peluso, I.; Rendina, R.; Digilio, A.; Furia, M.

The clot gene of Drosophila melanogaster encodes a conserved member of the thioredoxin-like protein superfamily

Mol. Genet. Genomics

268

692-697

2003

Drosophila melanogaster (Q9VMQ9)

12589444

671875

Kim, J.; Suh, H.; Kim, S.; Kim, K.; Ahn, C.; Yim, J.

Identification and characteristics of the structural gene for the Drosophila eye colour mutant sepia, encoding PDA synthase, a member of the Omega class glutathione S-transferases

Biochem. J.

398

451-460

2006

Drosophila melanogaster

16712527