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1.5.3.7: L-pipecolate oxidase

This is an abbreviated version!
For detailed information about L-pipecolate oxidase, go to the full flat file.

Word Map on EC 1.5.3.7

Reaction

L-pipecolate
+
O2
=
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate
+
H2O2

Synonyms

Fap1, L-pipecolate oxidase, L-pipecolic acid oxidase, L-PIPOX, pipecolate oxidase, PIPOX

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.7 L-pipecolate oxidase

General Information

General Information on EC 1.5.3.7 - L-pipecolate oxidase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
knockdown of the enzyme by small interference RNA abolishes pipecolate protection against hydrogen peroxide-induced cell death in HEK293 cells suggesting a critical role for this enzyme
physiological function
pipecolate metabolism leads to protection against H2O2 stress in mammalian cells. The enzyme is necessary for pipecolate protection