1.5.3.6: (R)-6-hydroxynicotine oxidase

This is an abbreviated version!
For detailed information about (R)-6-hydroxynicotine oxidase, go to the full flat file.

Word Map on EC 1.5.3.6

Reaction

(R)-6-hydroxynicotine
+
H2O
+
O2
=
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one
+
H2O2

Synonyms

6-HDNO, 6-hydroxy-D-nicotine oxidase, D-6-hydroxynicotine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.6 (R)-6-hydroxynicotine oxidase

Crystallization

Crystallization on EC 1.5.3.6 - (R)-6-hydroxynicotine oxidase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
a comparison of the substrate-binding modes of 6-hydroxy-D-nicotine oxidase and 6-hydroxy-L-nicotine oxidase, EC 1.5.3.5, based on models of complexes with the D-substrate, suggests that the two enzymes orient the enantiomeric substrates in mirror symmetry with respect to the plane of the flavin
-
fusion protein with glutathione S-transferase
-
hanging dropp method, the crystal structure of 6-hydroxy-D-nicotine oxidase is solved by X-ray diffraction analysis in three crystal forms at resolutions up to 1.9 A
-