1.5.3.6: (R)-6-hydroxynicotine oxidase

This is an abbreviated version!
For detailed information about (R)-6-hydroxynicotine oxidase, go to the full flat file.

Word Map on EC 1.5.3.6

Reaction

(R)-6-hydroxynicotine
+
H2O
+
O2
=
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one
+
H2O2

Synonyms

6-HDNO, 6-hydroxy-D-nicotine oxidase, D-6-hydroxynicotine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.6 (R)-6-hydroxynicotine oxidase

Activating Compound

Activating Compound on EC 1.5.3.6 - (R)-6-hydroxynicotine oxidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,6-dichlorophenolindophenol
-
the rate of the overall process is higher than with oxygen
glycerate-3-phosphate
-
activation of autocatalytical flavinylation
glycerol
-
activation of autocatalytical flavinylation of the enzyme at 45% v/v
glycerol-3-phosphate
methylene blue
-
the rate of the overall process is higher than with oxygen
phosphoenolpyruvate
-
activation of autocatalytical flavinylation, together with FAD protects the enzyme of proteolytic cleavage
sucrose
-
activation of autocatalytical flavinylation of the enzyme at 20%