1.5.3.25: fructosyl amine oxidase (glucosone-forming)
This is an abbreviated version!
For detailed information about fructosyl amine oxidase (glucosone-forming), go to the full flat file.
Reaction
Synonyms
AgaE-like protein, amadoriase, amadoriase I, amadoriase II, FaoA, FAOAo1, FAOAo2, FAOD, FAOD-Ao1, FAOD-Ao2, FAOX, FAOX-C, FAOX-II, FrlB, fructosyl amine:oxygen oxidoreductase, fructosyl amino acid oxidase, GAOA
ECTree
1.5.3.25 fructosyl amine oxidase (glucosone-forming)Advanced search results
results (
results (Substrates Products
Substrates Products on EC 1.5.3.25 - fructosyl amine oxidase (glucosone-forming)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-difructosyllysin + O2 + H2O
glucosone + lysine + H2O2
-
-
-
?
fructosyl-L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
glucose 6-phosphate + alpha-Boc-L-lysine + ?
fructosyl-6-phosphate alpha-Boc-L-lysine + ?
-
-
-
r
glucose 6-phosphate + glycine + ?
fructosyl-6-phosphate glycine + ?
-
-
-
r
glucose 6-phosphate + L-histidine + ?
fructosyl-6-phosphate L-histidine + ?
-
-
-
r
glucose 6-phosphate + L-lysine + ?
fructosyl-6-phosphate L-lysine + ?
-
-
-
r
glucose 6-phosphate + poly-L-lysine + ?
fructosyl-6-phosphate poly-L-lysine + ?
-
-
-
r
Nalpha-fructosyl L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
Nalpha-fructosyl-Nepsilon-acetyl-L-lysine + O2 + H2O
glucosone + Nepsilon-acetyl-L-lysine + H2O2
-
substrate of isoform amadoriase II
-
-
?
Nepsilon-(1-deoxy-D-fructos-1-yl)-L-lysine + O2 + H2O
? + L-lysine + H2O2
-
-
-
-
?
Nepsilon-fructosyl L-Lys-L-Leu + O2 + H2O
glucosone + L-Lys-L-Leu + H2O2
-
-
-
-
?
Nepsilon-fructosyl L-Lys-L-Phe + O2 + H2O
glucosone + L-Lys-L-Phe + H2O2
-
-
-
-
?
Nepsilon-fructosyl Nalpha-acetyl-L-Lys-D-Ala-L-Ala + O2 + H2O
glucosone + Nalpha-acetyl-L-Lys-D-Ala-L-Ala + H2O2
-
-
-
-
?
Nepsilon-fructosyl Nalpha-acetyl-L-Lys-D-D-Lys-Sar-Glu + O2 + H2O
glucosone + Nalpha-acetyl-L-Lys-D-Lys-Sar-Glu + H2O2
-
-
-
-
?
Nepsilon-fructosyl Nalpha-acetyl-L-lysine-N-methylamide + O2 + H2O
glucosone + acetyl-L-lysine-N-methylamide + H2O2
-
-
-
-
?
Nepsilon-fructosyl poly-L-lysine + O2 + H2O
glucosone + poly-L-lysine + H2O2
poor substrate
-
-
?
Nepsilon-fructosyl-Nalpha-benzyloxycarbonyl-L-lysine + O2 + H2O
glucosone + N-alpha-benzyloxycarbonyl-L-lysine + H2O2
Nepsilon-fructosyl-Nalpha-benzyloxycarbonyl-L-lysine + O2 + H2O
glucosone + N-alpha-benzyloxycarbonyl-L-valine + H2O2
-
-
-
-
?
Nepsilon-fructosyl-Nalpha-benzyloxycarbonyl-L-valine + O2 + H2O
glucosone + N-alpha-benzyloxycarbonyl-L-valine + H2O2
-
-
-
-
?
Nepsilon-fructosyl-Nalpha-t-butoxycarbonyl-L-lysine + O2 + H2O
glucosone + Nalpha-t-butoxycarbonyl-L-lysine + H2O2
-
-
-
-
?
S: Nepsilon-fructosyl Nalpha-benzyloxycarbonyl-L-lysine + O2 + H2O
glucosone + Nalpha-benzyloxycarbonyl-L-lysine + H2O2
-
-
-
?
epsilon-fructosyl-aminocaproate + O2 + H2O
glucosone + aminocaproate + H2O2
-
-
-
-
?
epsilon-fructosyl-aminocaproate + O2 + H2O
glucosone + aminocaproate + H2O2
Fusarium oxysporum f. sp. raphani NBRC 9972
-
-
-
-
?
fructosyl adamantanamine + O2 + H2O
glucosone + adamantanamine + H2O2
-
-
-
?
fructosyl adamantanamine + O2 + H2O
glucosone + adamantanamine + H2O2
poor substrate of isoform amadoriases I
-
-
?
fructosyl adamantanamine + O2 + H2O
glucosone + adamantanamine + H2O2
-
poor substrate of isoform amadoriases I
-
-
?
fructosyl glycine + O2 + H2O
glucosone + glycine + H2O2
-
-
-
?
fructosyl glycine + O2 + H2O
glucosone + glycine + H2O2
-
-
-
?
fructosyl glycine + O2 + H2O
glucosone + glycine + H2O2
-
-
-
?
fructosyl glycine + O2 + H2O
glucosone + glycine + H2O2
poor substrate of isoform amadoriases I
-
-
?
fructosyl L-alanine + O2 + H2O
glucosone + L-alanine + H2O2
-
-
-
-
?
fructosyl L-alanine + O2 + H2O
glucosone + L-alanine + H2O2
Fusarium oxysporum f. sp. raphani NBRC 9972
-
-
-
-
?
fructosyl L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
fructosyl L-phenylalanine + O2 + H2O
glucosone + L-phenylalanine + H2O2
-
-
-
?
fructosyl L-phenylalanine + O2 + H2O
glucosone + L-phenylalanine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
Fusarium oxysporum f. sp. raphani NBRC 9972
-
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
-
-
-
?
fructosyl L-valine + O2 + H2O
glucosone + L-valine + H2O2
poor substrate of isoform amadoriases I
-
-
?
fructosyl poly-L-lysine + O2 + H2O
glucosone + poly-L-lysine + H2O2
-
-
-
?
fructosyl poly-L-lysine + O2 + H2O
glucosone + poly-L-lysine + H2O2
-
-
-
-
?
fructosyl propylamine + O2 + H2O
glucosone + propylamine + H2O2
-
-
-
?
fructosyl propylamine + O2 + H2O
glucosone + propylamine + H2O2
-
-
-
-
?
gamma-fructosyl-aminobutanoate + O2 + H2O
glucosone + aminobutanoate + H2O2
-
-
-
-
?
gamma-fructosyl-aminobutanoate + O2 + H2O
glucosone + aminobutanoate + H2O2
Fusarium oxysporum f. sp. raphani NBRC 9972
-
-
-
-
?
Nepsilon-fructosyl L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
Nepsilon-fructosyl L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
Nepsilon-fructosyl-L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
-
-
-
?
Nepsilon-fructosyl-L-lysine + O2 + H2O
glucosone + L-lysine + H2O2
poor substrate of isoform amadoriases I
-
-
?
Nepsilon-fructosyl-Nalpha-benzyloxycarbonyl-L-lysine + O2 + H2O
glucosone + N-alpha-benzyloxycarbonyl-L-lysine + H2O2
-
-
-
-
?
Nepsilon-fructosyl-Nalpha-benzyloxycarbonyl-L-lysine + O2 + H2O
glucosone + N-alpha-benzyloxycarbonyl-L-lysine + H2O2
Fusarium oxysporum f. sp. raphani NBRC 9972
-
-
-
-
?
additional information
?
-
no substrates: glycated protein or Nepsilon-fructosyl-L-lysine, Nepsilon-fructosyl-Nalpha-(benzyloxycarbonyl)-L-lysine
-
-
-
additional information
?
-
-
no substrates: glycated protein or Nepsilon-fructosyl-L-lysine, Nepsilon-fructosyl-Nalpha-(benzyloxycarbonyl)-L-lysine
-
-
-
additional information
?
-
fructosyl-alpha-L-amino acids are the substrate having the highest susceptibility to the enzyme, but N-fructosyl derivatives of other materials, such as p-amino acids, L-imino acids, D-amino acids, alkyl amines, and ammonia, show almost no susceptibility
-
-
-
additional information
?
-
no substrate: Nepsilon-D-fructosyl-Nalpha-formyl-L-lysine
-
-
-
additional information
?
-
-
Kmvalue decreases with the length of peptide substrate, being slightly reduced for dipeptides, and is around 10 mM for tri- and tetrapeptides. Glycated proteins are not substrates of the enzyme, but when amadoriase I is added during the glycation reaction, a significant reduction of Amadori product formation is observed on both peptides and proteins
-
-
-
additional information
?
-
no substrates: fructosyl L-valine, L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
no substrates: fructosyl L-valine, L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
-
no substrates: fructosyl L-valine, L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
no substrates: L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
no substrates: L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
-
no substrates: L-Pipecolate, sarcosine, and L-proline
-
-
-
additional information
?
-
FrlB amadoriase is capable of catalyzing in the reverse reaction the formation of Amadori products on a number of free amino acids and on polypeptides as well
-
-
-
