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1.5.3.25: fructosyl amine oxidase (glucosone-forming)

This is an abbreviated version!
For detailed information about fructosyl amine oxidase (glucosone-forming), go to the full flat file.

Reaction

a 2-[(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexylidene]amine
+
H2O
=
D-glucosone
+
an amine

Synonyms

AgaE-like protein, amadoriase, amadoriase I, amadoriase II, FaoA, FAOAo1, FAOAo2, FAOD, FAOD-Ao1, FAOD-Ao2, FAOX, FAOX-C, FAOX-II, FrlB, fructosyl amine:oxygen oxidoreductase, fructosyl amino acid oxidase, GAOA

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.25 fructosyl amine oxidase (glucosone-forming)

Application

Application on EC 1.5.3.25 - fructosyl amine oxidase (glucosone-forming)

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
development of a continuous, coupled enzyme assay
synthesis
-
addition of amadoriase I during peptide glycation reaction reduces the formation of Amadori products up to 80%. The effect is more evident for hydrophobic peptides. In protein-glucose systems, the effect is dependent on the molecular weight and steric hindrance being negligible for BSA and at a maximum for insulin