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1.5.3.16: spermine oxidase

This is an abbreviated version!
For detailed information about spermine oxidase, go to the full flat file.

Word Map on EC 1.5.3.16

Reaction

spermine
+
O2
+
H2O
=
spermidine
+
3-aminopropanal
+
H2O2

Synonyms

AtPAO1, AtPAO4, AtPAO5, EC 1.5.3.11, Fms1 protein, GhPAO, hSMO, MmSMO, mSMO, mSMOalpha, mSMOmu, PAO, PAO1, PAO4, PAO5, PAO6, PAO7, PAOh1, PAOh1/SMO, SelPAO5, SMO, SMO(PAOh1), SMO/PAOh1, SMO5, SMOX, spermine oxidase, Spm oxidase, thermospermine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.16 spermine oxidase

Source Tissue

Source Tissue on EC 1.5.3.16 - spermine oxidase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
the antiproliferative effects of analogue N1,N1-bis(ethyl)norspermine in MDA-MB-231 cells are mediated in part through the production of H2O2 by SMO(PAOh1) and by the export of acetylated polyamines formed by the activity of spermidine/spermine N1-acetyltransferase
Manually annotated by BRENDA team
hepatocellular carcinoma cell
Manually annotated by BRENDA team
splice variant mSMO
Manually annotated by BRENDA team
splice variant mSMO
Manually annotated by BRENDA team
-
mononuclear inflammatory cells
Manually annotated by BRENDA team
-
tissues from patients diagnosed with prostate cancer and prostatic intraepithelial neoplasia exhibit, on average, locally increased spermine oxidase (SMO) expression in regions of prostatic disease and higher overall SMO expression in prostatic epithelial cells compared to healthy individuals
Manually annotated by BRENDA team
poor activity, splice variant mSMO
Manually annotated by BRENDA team
splice variant mSMO
Manually annotated by BRENDA team
monocytic cell line
Manually annotated by BRENDA team
additional information