1.5.3.16: spermine oxidase
This is an abbreviated version!
For detailed information about spermine oxidase, go to the full flat file.
Word Map on EC 1.5.3.16
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1.5.3.16
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polyamine
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putrescine
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acetylpolyamine
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back-conversion
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n1-acetylspermine
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n1-acetylpolyamine
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3-aminopropanal
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acrolein
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benspm
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medicine
- 1.5.3.16
- polyamine
- putrescine
-
acetylpolyamine
-
back-conversion
- n1-acetylspermine
-
n1-acetylpolyamine
- 3-aminopropanal
- acrolein
-
benspm
- medicine
Reaction
Synonyms
AtPAO1, AtPAO4, AtPAO5, EC 1.5.3.11, Fms1 protein, GhPAO, hSMO, MmSMO, mSMO, mSMOalpha, mSMOmu, PAO, PAO1, PAO4, PAO5, PAO6, PAO7, PAOh1, PAOh1/SMO, SelPAO5, SMO, SMO(PAOh1), SMO/PAOh1, SMO5, SMOX, spermine oxidase, Spm oxidase, thermospermine oxidase
ECTree
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Source Tissue
Source Tissue on EC 1.5.3.16 - spermine oxidase
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the antiproliferative effects of analogue N1,N1-bis(ethyl)norspermine in MDA-MB-231 cells are mediated in part through the production of H2O2 by SMO(PAOh1) and by the export of acetylated polyamines formed by the activity of spermidine/spermine N1-acetyltransferase
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tissues from patients diagnosed with prostate cancer and prostatic intraepithelial neoplasia exhibit, on average, locally increased spermine oxidase (SMO) expression in regions of prostatic disease and higher overall SMO expression in prostatic epithelial cells compared to healthy individuals
additional information
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SMO transcript accumulation and enzymatic activity increases during C2C12 cell differentiation and correlates with the decrease of spermine content. Increased spermine oxidase (SMO) activity is a differentiation marker of myogenic C2C12 cells
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young, in anthers and in particular in the microspores and the tapetum, microspore staining is gradually decreased during flower development, anther staining is finally restricted to the antherfilament junction
expressed at higher level all over young seedlings including roots
expressed at higher level all over young seedlings including roots
isozyme AtPAO4 transcript is abundantly expressed in roots, flowers and greening cotyledons, but more poorly expressed in other tissues
additional information
in the mature stage expression is ubiquitous with rather lower level in stem
additional information
in the mature stage expression is ubiquitous with rather lower level in stem
additional information
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in the mature stage expression is ubiquitous with rather lower level in stem
additional information
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expression pattern of AtPAO1 during seedling and flower growth and development through analysis of promoter activity in AtPAO::GUS transgenic Arabidopsis thaliana plants, a strong AtPAO1-related GUS signal is observed in very young, completely closed flower buds. AtPAO1 is mostly expressed in the transition region between the meristematic and the elongation zone of roots and anther tapetum
additional information
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immunohistochemic detection of enzyme expression in different tissue during inflammation, overview